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Katriana Nugent

Explore the profile of Katriana Nugent including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 358
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Recent Articles
1.
Gajula R, Chettiar S, Williams R, Nugent K, Kato Y, Wang H, et al.
Neoplasia . 2024 Oct; 57():101010. PMID: 39389677
No abstract available.
2.
Wang X, Raman N, Lemtiri-Chlieh G, Chang J, Jagtap S, Chowdhury D, et al.
Mol Cancer Ther . 2023 Feb; 22(4):519-528. PMID: 36752776
Extra copies of centrosomes are frequently observed in cancer cells. To survive and proliferate, cancer cells have developed strategies to cluster extra-centrosomes to form bipolar mitotic spindles. The aim of...
3.
Taparra K, Wang H, Malek R, Lafargue A, Barbhuiya M, Wang X, et al.
J Clin Invest . 2018 Aug; 128(11):4924-4937. PMID: 30130254
Mutant KRAS drives glycolytic flux in lung cancer, potentially impacting aberrant protein glycosylation. Recent evidence suggests aberrant KRAS drives flux of glucose into the hexosamine biosynthetic pathway (HBP). HBP is...
4.
Vendetti F, Karukonda P, Clump D, Teo T, Lalonde R, Nugent K, et al.
J Clin Invest . 2018 Jun; 128(9):3926-3940. PMID: 29952768
DNA-damaging chemotherapy and radiation therapy are integrated into the treatment paradigm of the majority of cancer patients. Recently, immunotherapy that targets the immunosuppressive interaction between programmed death 1 (PD-1) and...
5.
Benzon B, Glavaris S, Simons B, Hughes R, Ghabili K, Mullane P, et al.
Prostate Cancer Prostatic Dis . 2018 Mar; 21(1):126-136. PMID: 29556048
Background: Prostate cancer remains the second leading cause of cancer related death in men. Immune check point blocking antibodies have revolutionized treatment of multiple solid tumors, but results in prostate...
6.
Yochum Z, Cades J, Mazzacurati L, Neumann N, Khetarpal S, Chatterjee S, et al.
Mol Cancer Res . 2017 Aug; 15(12):1764-1776. PMID: 28851812
TWIST1, an epithelial-mesenchymal transition (EMT) transcription factor, is critical for oncogene-driven non-small cell lung cancer (NSCLC) tumorigenesis. Given the potential of TWIST1 as a therapeutic target, a chemical-bioinformatic approach using...
7.
Malek R, Gajula R, Williams R, Nghiem B, Simons B, Nugent K, et al.
Cancer Res . 2017 May; 77(12):3181-3193. PMID: 28484075
TWIST1 is a transcription factor critical for development that can promote prostate cancer metastasis. During embryonic development, TWIST1 and HOXA9 are coexpressed in mouse prostate and then silenced postnatally. Here...
8.
Zhang B, Wong J, Iordachita I, Reyes J, Nugent K, Tran P, et al.
Radiat Res . 2016 Nov; 186(6):592-601. PMID: 27869556
In response to the limitations of computed tomography (CT) and cone-beam CT (CBCT) in irradiation guidance, especially for soft-tissue targets without the use of contrast agents, our group developed a...
9.
Xie M, Vesuna F, Tantravedi S, Bol G, Heerma van Voss M, Nugent K, et al.
Cancer Res . 2016 Sep; 76(21):6340-6350. PMID: 27634756
Despite advances in diagnosis and treatment, prostate cancer is the most prevalent cancer in males and the second highest cause of cancer-related mortality. We identified an RNA helicase gene, DDX3...
10.
Gajula R, Chettiar S, Williams R, Nugent K, Kato Y, Wang H, et al.
Neoplasia . 2015 Jan; 17(1):16-31. PMID: 25622896
The TWIST1 gene has diverse roles in development and pathologic diseases such as cancer. TWIST1 is a dimeric basic helix-loop-helix (bHLH) transcription factor existing as TWIST1-TWIST1 or TWIST1-E12/47. TWIST1 partner...