Kathryn M Lenz
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Explore the profile of Kathryn M Lenz including associated specialties, affiliations and a list of published articles.
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30
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1510
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Recent Articles
11.
Joshi A, Page C, Damante M, Dye C, Haim A, Leuner B, et al.
Horm Behav
. 2019 May;
113:76-84.
PMID: 31054843
Early life stress leads to long lasting effects on behavior. Neuroimmune cells have been implicated as key mediators of experience-induced changes in brain and behavioral development, in that they are...
12.
Lenz K, Pickett L, Wright C, Galan A, McCarthy M
Sci Rep
. 2019 Mar;
9(1):4837.
PMID: 30886382
Sexual differentiation is the early life process by which the brain is prepared for male or female typical behaviors, and is directed by sex chromosomes, hormones and early life experiences....
13.
Nelson L, Saulsbery A, Lenz K
Prog Neurobiol
. 2018 Sep;
176:103-119.
PMID: 30193820
Brain sex differences are programmed largely by sex hormone secretions and direct sex chromosome effects in early life, and are subsequently modulated by early life experiences. The brain's resident immune...
14.
Lenz K, Pickett L, Wright C, Davis K, Joshi A, McCarthy M
J Neurosci
. 2018 Aug;
38(37):8044-8059.
PMID: 30093566
Many sex differences in brain and behavior are programmed during development by gonadal hormones, but the cellular mechanisms are incompletely understood. We found that immune-system-derived mast cells are a primary...
15.
Microglia and Beyond: Innate Immune Cells As Regulators of Brain Development and Behavioral Function
Lenz K, Nelson L
Front Immunol
. 2018 May;
9:698.
PMID: 29706957
Innate immune cells play a well-documented role in the etiology and disease course of many brain-based conditions, including multiple sclerosis, Alzheimer's disease, traumatic brain and spinal cord injury, and brain...
16.
McCarthy M, Nugent B, Lenz K
Nat Rev Neurosci
. 2017 Jun;
18(8):471-484.
PMID: 28638119
The study of sex differences in the brain is a topic of neuroscientific study that has broad reaching implications for culture, society and biomedical science. Recent research in rodent models...
17.
Nugent B, Wright C, Shetty A, Hodes G, Lenz K, Mahurkar A, et al.
Nat Neurosci
. 2017 May;
20(6):896.
PMID: 28542152
No abstract available.
18.
Nelson L, Warden S, Lenz K
Brain Behav Immun
. 2017 Mar;
64:11-22.
PMID: 28341582
Microglia regulate brain development through many processes, such as promoting neurogenesis, supporting cell survival, and phagocytizing progenitor, newly-born, and dying cells. Many of these same developmental processes show robust sex...
19.
Nelson L, Lenz K
J Neurosci Res
. 2016 Nov;
95(1-2):447-461.
PMID: 27870450
Sexual differentiation of the brain occurs early in life as a result of sex-typical hormone action and sex chromosome effects. Immunocompetent cells are being recognized as underappreciated regulators of sex...
20.
Haim A, Julian D, Albin-Brooks C, Brothers H, Lenz K, Leuner B
Brain Behav Immun
. 2016 Oct;
59:67-78.
PMID: 27686844
During pregnancy and the postpartum period, the adult female brain is remarkably plastic exhibiting modifications of neurons, astrocytes and oligodendrocytes. However, little is known about how microglia, the brain's innate...