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Bridget M Nugent

Explore the profile of Bridget M Nugent including associated specialties, affiliations and a list of published articles. Areas
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Citations 1599
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Recent Articles
1.
Rock K, Folts L, Zierden H, Marx-Rattner R, Leu N, Nugent B, et al.
Sci Rep . 2023 Nov; 13(1):21082. PMID: 38030664
The genetic material encoded on X and Y chromosomes provides the foundation by which biological sex differences are established. Epigenetic regulators expressed on these sex chromosomes, including Kdm6a (Utx), Kdm5c,...
2.
Zhou S, Qi K, Nugent B, Bersoff-Matcha S, Struble K
AIDS . 2023 Feb; 37(6):895-903. PMID: 36728423
Objectives: To examine female participation and the observed efficacy and safety by sex from phase 3 HIV-1 trials submitted to the United States Food and Drug Administration (FDA) to support...
3.
Vasisht K, Nugent B, Woodcock J
Med . 2022 May; 2(5):456-459. PMID: 35590224
Recruiting and retaining diverse populations in clinical research is critically important. Over the years, we have seen improvements in the representation of women in clinical trials submitted in FDA marketing...
4.
Nugent B, Madabushi R, Buch B, Peiris V, Crentsil V, Miller V, et al.
Pharm Stat . 2021 Aug; 20(5):929-938. PMID: 34396690
Differences in patient characteristics, including age, sex, and race influence the safety and effectiveness of drugs, biologic products, and medical devices. Here we provide a summary of the topics discussed...
5.
Cisse Y, Chan J, Nugent B, Banducci C, Bale T
Placenta . 2020 Sep; 100:164-170. PMID: 32980048
Introduction: Despite a wealth of epidemiological evidence that cumulative parental lifetime stress experiences prior to conception are determinant of offspring developmental trajectories, there is a lack of insight on how...
6.
Chan J, Morgan C, Leu N, Shetty A, Cisse Y, Nugent B, et al.
Nat Commun . 2020 Mar; 11(1):1499. PMID: 32198406
Extracellular vesicles (EVs) are a unique mode of intercellular communication capable of incredible specificity in transmitting signals involved in cellular function, including germ cell maturation. Spermatogenesis occurs in the testes,...
7.
Nugent B, Stiver K, Hofmann H, Alonzo S
Mol Ecol . 2018 Dec; 28(15):3464-3481. PMID: 30586201
While extensive research has focused on how social interactions evolve, the fitness consequences of the neuroendocrine mechanisms underlying these interactions have rarely been documented, especially in the wild. Here, we...
8.
Nugent B, ODonnell C, Epperson C, Bale T
Nat Commun . 2018 Jul; 9(1):2555. PMID: 29967448
Although sex biases in disease presentation are well documented, the mechanisms mediating vulnerability or resilience to diseases are unknown. In utero insults are more likely to produce detrimental health outcomes...
9.
Chan J, Nugent B, Bale T
Biol Psychiatry . 2017 Dec; 83(10):886-894. PMID: 29198470
Parental stress exposures are implicated in the risk for offspring neurodevelopmental and neuropsychiatric disorders, prompting critical examination of preconception and prenatal periods as vulnerable to environmental insults such as stress....
10.
McCarthy M, Nugent B, Lenz K
Nat Rev Neurosci . 2017 Jun; 18(8):471-484. PMID: 28638119
The study of sex differences in the brain is a topic of neuroscientific study that has broad reaching implications for culture, society and biomedical science. Recent research in rodent models...