Dale R Sengelaub
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Explore the profile of Dale R Sengelaub including associated specialties, affiliations and a list of published articles.
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64
Citations
917
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Recent Articles
1.
Hibbard E, Du X, Zhang Y, Xu X, Deng L, Sengelaub D
Restor Neurol Neurosci
. 2024 Aug;
42(2):151-165.
PMID: 39213108
Background: Spinal cord injury (SCI) results in lesions that destroy tissue and spinal tracts, leading to deficits in locomotor and autonomic function. We have previously shown that after SCI, surviving...
2.
Zhou L, Venkudusamy K, Hibbard E, Montoya Y, Olivarez A, Yang C, et al.
Neural Regen Res
. 2024 Jun;
20(9):2667-2681.
PMID: 38934383
JOURNAL/nrgr/04.03/01300535-202509000-00028/figure1/v/2024-11-05T132919Z/r/image-tiff Successful polyethylene glycol fusion (PEG-fusion) of severed axons following peripheral nerve injuries for PEG-fused axons has been reported to: (1) rapidly restore electrophysiological continuity; (2) prevent distal Wallerian Degeneration...
3.
Hibbard E, Zhou L, Yang C, Venkudusamy K, Montoya Y, Olivarez A, et al.
Neural Regen Res
. 2024 Jun;
20(7):2095-2107.
PMID: 38845228
JOURNAL/nrgr/04.03/01300535-202507000-00030/figure1/v/2024-09-09T124005Z/r/image-tiff Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions; behavioral recovery is typically poor. We used a plasmalemmal...
4.
Meadows R, Richards S, Kitsis M, Brown T, Jones K, Sengelaub D
Restor Neurol Neurosci
. 2024 Feb;
41(5-6):241-256.
PMID: 38363624
Background: Peripheral nerve injury (PNI) is the most common type of nerve trauma yet, while injured motoneurons exhibit a robust capacity for regeneration, behavioral recovery is protracted and typically poor....
5.
Arnold A, Chen X, Grzybowski M, Ryan J, Sengelaub D, Mohanroy T, et al.
bioRxiv
. 2023 Feb;
PMID: 36798326
Background: We have generated a rat model similar to the Four Core Genotypes mouse model, allowing comparison of XX and XY rats with the same type of gonad. The model...
6.
Hibbard E, Sengelaub D
Front Cell Neurosci
. 2022 Apr;
16:852933.
PMID: 35431811
Peripheral nerve injuries are the most common type of nerve trauma. We have been working with a novel repair technique using a plasmalemmal fusogen, polyethylene glycol (PEG), to re-fuse the...
7.
Chew C, Sengelaub D
Dev Neurobiol
. 2020 Dec;
81(1):22-35.
PMID: 33289343
Motoneuron loss is a severe medical problem that can result in loss of motor control and eventually death. We have previously demonstrated that partial motoneuron loss can result in dendritic...
8.
Chew C, Sengelaub D
Neural Regen Res
. 2020 Jan;
15(8):1373-1376.
PMID: 31997795
Injuries to spinal motoneurons manifest in a variety of forms, including damage to peripheral axons, neurodegenerative disease, or direct insult centrally. Such injuries produce a variety of negative structural and...
9.
Ghergherehchi C, Hibbard E, Mikesh M, Bittner G, Sengelaub D
PLoS One
. 2019 Oct;
14(10):e0223443.
PMID: 31584985
Polyethylene glycol repair (PEG-fusion) of severed sciatic axons restores their axoplasmic and membrane continuity, prevents Wallerian degeneration, maintains muscle fiber innervation, and greatly improves recovery of voluntary behaviors. We examined...
10.
Chew C, Sengelaub D
Neurorehabil Neural Repair
. 2019 Jul;
33(8):656-667.
PMID: 31286830
. Motoneuron loss is a severe medical problem that can result in loss of motor control and eventually death. We have previously demonstrated that partial motoneuron loss can result in...