Katherine U Tavasoli
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Explore the profile of Katherine U Tavasoli including associated specialties, affiliations and a list of published articles.
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4
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2
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Recent Articles
1.
Sheedy C, Chowdhury S, Ali B, Miyamoto J, Pang E, Bacal J, et al.
bioRxiv
. 2024 Dec;
PMID: 39713301
The PEX1/PEX6 AAA-ATPase is required for the biogenesis and maintenance of peroxisomes. Mutations in and disrupt peroxisomal matrix protein import and are the leading cause of Peroxisome Biogenesis Disorders (PBDs)....
2.
Vu J, Tavasoli K, Sheedy C, Chowdhury S, Mandjikian L, Bacal J, et al.
J Cell Biol
. 2024 Jul;
223(10).
PMID: 38967608
Peroxisomes are membrane-bound organelles harboring metabolic enzymes. In humans, peroxisomes are required for normal development, yet the genes regulating peroxisome function remain unclear. We performed a genome-wide CRISPRi screen to...
3.
Vu J, Tavasoli K, Mandjikian L, Sheedy C, Bacal J, Morrissey M, et al.
bioRxiv
. 2024 Feb;
PMID: 38352406
Peroxisomes are membrane-bound organelles harboring metabolic enzymes. In humans, peroxisomes are required for normal development, yet the genes regulating peroxisome function remain unclear. We performed a genome-wide CRISPRi screen to...
4.
Ghasemi H, Bacal J, Yoon A, Tavasoli K, Cruz C, Vu J, et al.
Nat Biotechnol
. 2023 Feb;
41(10):1398-1404.
PMID: 36849829
We describe a strategy to boost the efficiency of gene editing via homology-directed repair (HDR) by covalently modifying the template DNA with interstrand crosslinks. Crosslinked templates (xHDRTs) increase Cas9-mediated editing...