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Katherine Quesnel

Explore the profile of Katherine Quesnel including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Hutchenreuther J, Nguyen J, Quesnel K, Vincent K, Petitjean L, Bourgeois S, et al.
Cancer Res Commun . 2024 Feb; 4(2):556-570. PMID: 38363129
Significance: In human patients, the expression of proangiogenic matricellular protein CCN1 in CAFs correlates positively with expression of stroma and angiogenic markers and progressive disease/resistance to checkpoint inhibitor therapy. In...
2.
Dieters-Castator D, Dantonio P, Piaseczny M, Zhang G, Liu J, Kuljanin M, et al.
Neoplasia . 2021 Mar; 23(4):375-390. PMID: 33784590
The tumor microenvironment (TME) is an important mediator of breast cancer progression. Cancer-associated fibroblasts constitute a major component of the TME and may originate from tissue-associated fibroblasts or infiltrating mesenchymal...
3.
Quesnel K, Shi-Wen X, Hutchenreuther J, Xiao Y, Liu S, Peidl A, et al.
Matrix Biol Plus . 2021 Feb; 3:100009. PMID: 33543008
The microenvironment contributes to the excessive connective tissue deposition that characterizes fibrosis. Members of the CCN family of matricellular proteins are secreted by fibroblasts into the fibrotic microenvironment; however, the...
4.
Shi-Wen X, Racanelli M, Ali A, Simon A, Quesnel K, Stratton R, et al.
J Cell Commun Signal . 2021 Jan; 15(1):71-80. PMID: 33398723
Fibrosis is perpetuated by an autocrine, pro-adhesive signaling loop maintained by the synthetic and contractile abilities of myofibroblasts and the stiff, highly-crosslinked extracellular matrix. Transcriptional complexes that are exquisitely responsive...
5.
Tsang M, Quesnel K, Vincent K, Hutchenreuther J, Postovit L, Leask A
Am J Pathol . 2019 Oct; 190(1):206-221. PMID: 31610176
Tumor stroma resembles a fibrotic microenvironment, being characterized by the presence of myofibroblast-like cancer-associated fibroblasts (CAFs). In wild-type mice injected with melanoma cells, we show that the stem cell transcription...
6.
Bedore J, Quesnel K, Quinonez D, Seguin C, Leask A
J Cell Commun Signal . 2016 May; 10(2):137-42. PMID: 27173473
Degeneration of the intervertebral disc (IVD) is a major underlying contributor to back pain-the single leading cause of disability worldwide. However, we possess a limited understanding of the etiology underlying...