Katherine Nathanson
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Explore the profile of Katherine Nathanson including associated specialties, affiliations and a list of published articles.
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24
Citations
467
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Recent Articles
1.
Ping J, Jia G, Cai Q, Guo X, Tao R, Ambrosone C, et al.
Nat Commun
. 2024 May;
15(1):3718.
PMID: 38697998
African-ancestry (AA) participants are underrepresented in genetics research. Here, we conducted a transcriptome-wide association study (TWAS) in AA female participants to identify putative breast cancer susceptibility genes. We built genetic...
2.
Brown T, Yablonovitch A, Till J, Yen J, Kiedrowski L, Hood R, et al.
Clin Cancer Res
. 2023 Jul;
29(24):5207-5216.
PMID: 37486343
Purpose: PARP inhibitors (PARPi) provide an effective maintenance option for patients with BRCA- or PALB2-mutated pancreatic cancer. However, mechanisms of PARPi resistance and optimal post-PARPi therapeutic strategies are poorly characterized....
3.
Stolarova L, Kleiblova P, Zemankova P, Stastna B, Janatova M, Soukupova J, et al.
Clin Cancer Res
. 2023 Jul;
29(16):3037-3050.
PMID: 37449874
Purpose: Germline pathogenic variants in CHEK2 confer moderately elevated breast cancer risk (odds ratio, OR ∼ 2.5), qualifying carriers for enhanced breast cancer screening. Besides pathogenic variants, dozens of missense...
4.
Rebecca V, Jagirdar K, Portuallo M, Wei M, Wilhide M, Bravo J, et al.
Res Sq
. 2023 May;
PMID: 37131684
Patients with metastatic acral lentiginous melanoma (ALM) suffer worse outcomes relative to patients with other forms of cutaneous melanoma (CM), and do not benefit as well to approved melanoma therapies....
5.
Rebecca V, Xiao M, Kossenkov A, Godok T, Brown G, Fingerman D, et al.
bioRxiv
. 2023 Jan;
PMID: 36711814
Resistance to combination BRAF/MEK inhibitor (BRAFi/MEKi) therapy arises in nearly every patient with melanoma, despite promising initial responses. Achieving cures in this expanding BRAFi/MEKi-resistant cohort represents one of the greatest...
6.
Pace L, Tung N, Lee Y, Hamilton J, Gabriel C, Revette A, et al.
J Gen Intern Med
. 2021 Jun;
37(8):1862-1869.
PMID: 34173196
Purpose: Engaging primary care providers (PCPs) in BRCA1/2 testing and results disclosure would increase testing access. The BRCA Founder OutReach (BFOR) study is a prospective study of BRCA1/2 founder mutation...
7.
Reiss K, Mick R, OHara M, Teitelbaum U, Karasic T, Schneider C, et al.
J Clin Oncol
. 2021 May;
39(22):2497-2505.
PMID: 33970687
Purpose: Olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor (PARPi), is approved as maintenance therapy for patients with advanced pancreatic cancer (PC) and a germline or pathogenic variant (PV). This investigator-initiated,...
8.
Liu D, Lin J, Robitschek E, Kasumova G, Heyde A, Shi A, et al.
Nat Med
. 2021 May;
27(6):985-992.
PMID: 33941922
Despite initial responses, most melanoma patients develop resistance to immune checkpoint blockade (ICB). To understand the evolution of resistance, we studied 37 tumor samples over 9 years from a patient...
9.
Ostrowski P, Zachariou A, Loveday C, Beleza-Meireles A, Bertoli M, Dean J, et al.
Am J Med Genet C Semin Med Genet
. 2019 Nov;
181(4):557-564.
PMID: 31721432
CHD8 has been reported as an autism susceptibility/intellectual disability gene but emerging evidence suggests that it additionally causes an overgrowth phenotype. This study reports 27 unrelated patients with pathogenic or...
10.
Kofke W, Ren Y, Augoustides J, Li H, Nathanson K, Siman R, et al.
Front Neurol
. 2018 Jul;
9:497.
PMID: 29997569
Neuroprotection studies are generally unable to demonstrate efficacy in humans. Our specific hypothesis is that multiple pathophysiologic pathways, of variable importance, contribute to ischemic brain damage. As a corollary to...