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Katherine K Matthay

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Articles 184
Citations 9415
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Recent Articles
1.
Chesler L, Schlieve C, Goldenberg D, Kenney A, Kim G, McMillan A, et al.
Cancer Res . 2024 Oct; 84(19):3311. PMID: 39350668
No abstract available.
2.
Kumar P, Koach J, Nekritz E, Mukherjee S, Braun B, Dubois S, et al.
EJNMMI Res . 2024 Jun; 14(1):54. PMID: 38869684
Background: Neuroblastoma is the most common extra-cranial pediatric solid tumor. I-metaiodobenzylguanidine (MIBG) is a targeted radiopharmaceutical highly specific for neuroblastoma tumors, providing potent radiotherapy to widely metastatic disease. Aurora kinase...
3.
Barr E, Naranjo A, Twist C, Tenney S, Schmidt M, London W, et al.
Pediatr Blood Cancer . 2024 Jun; 71(8):e31089. PMID: 38822537
Background: We previously reported excellent three-year overall survival (OS) for patients with newly diagnosed intermediate-risk neuroblastoma treated with a biology- and response-based algorithm on the Children's Oncology Group study ANBL0531....
4.
Kumar P, Willard V, Embry L, Naranjo A, LaBarre B, Matthay K, et al.
Pediatr Blood Cancer . 2024 May; 71(7):e31039. PMID: 38689540
Background: Opsoclonus-myoclonus-ataxia syndrome (OMAS) is a rare autoimmune disorder of the nervous system presenting with abnormal eye and limb movements, altered gait, and increased irritability. Two to four percent of...
5.
Huang M, Fang W, Farrel A, Li L, Chronopoulos A, Nasholm N, et al.
Cell Rep . 2024 Mar; 43(3):113927. PMID: 38451815
Neuroblastoma is the most common extracranial solid tumor of childhood. While MYCN and mutant anaplastic lymphoma kinase (ALK) cooperate in tumorigenesis, how ALK contributes to tumor formation remains unclear. Here,...
6.
Kumar P, Koach J, Nekritz E, Mukherjee S, Braun B, Dubois S, et al.
Res Sq . 2024 Feb; PMID: 38313265
Background: Neuroblastoma is the most common extra-cranial pediatric solid tumor. I-metaiodobenzylguanidine (MIBG) is a targeted radiopharmaceutical highly specific for neuroblastoma tumors, providing potent radiotherapy to widely metastatic disease. Aurora kinase...
7.
Hogarty M, Ziegler D, Franson A, Chi Y, Tsao-Wei D, Liu K, et al.
Br J Cancer . 2024 Jan; 130(5):788-797. PMID: 38200233
Background: MYC genes regulate ornithine decarboxylase (Odc) to increase intratumoral polyamines. We conducted a Phase I trial [NCT02030964] to determine the maximum tolerated dose (MTD) of DFMO, an Odc inhibitor,...
8.
Chang D, Oh T, Roland J, Matthay K, Vo K, Edwards C, et al.
J Neurosurg Pediatr . 2023 Dec; 33(3):245-255. PMID: 38100763
Objective: Neuroblastoma with spinal involvement accounts for up to 30% of pediatric spinal tumors and can cause profound neurological deficits. Chemotherapy is the preferred treatment option, but in select patients...
9.
Batra V, Gikandi A, Pawel B, Martinez D, Granger M, Marachelian A, et al.
Pediatr Blood Cancer . 2023 Oct; 71(1):e30743. PMID: 37885116
Background: Prior studies suggest that norepinephrine transporter (NET) and vesicular monoamine transporter 2 (VMAT2) mediate meta-iodobenzylguanidine (MIBG) uptake and retention in neuroblastoma tumors. We evaluated the relationship between NET and...
10.
Rosenberg M, Greenstein E, Buchkovich M, Peres A, Santoni-Rugiu E, Yang L, et al.
Cell Rep . 2023 Aug; 42(8):112879. PMID: 37537844
Neuroblastoma is a lethal childhood solid tumor of developing peripheral nerves. Two percent of children with neuroblastoma develop opsoclonus myoclonus ataxia syndrome (OMAS), a paraneoplastic disease characterized by cerebellar and...