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Katherine H Gotlinger

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Articles 22
Citations 1346
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Recent Articles
1.
Soler A, Hunter I, Joseph G, Hutcheson R, Hutcheson B, Yang J, et al.
J Mol Cell Cardiol . 2018 Apr; 121:308. PMID: 29625729
No abstract available.
2.
Soler A, Hunter I, Joseph G, Hutcheson R, Hutcheson B, Yang J, et al.
J Mol Cell Cardiol . 2018 Feb; 117:88-99. PMID: 29428638
Arterial stiffness plays a causal role in development of systolic hypertension. 20-hydroxyeicosatetraeonic acid (20-HETE), a cytochrome P450 (CYP450)-derived arachidonic acid metabolite, is known to be elevated in resistance arteries in...
3.
Bowden J, Heckert A, Ulmer C, Jones C, Koelmel J, Abdullah L, et al.
J Lipid Res . 2017 Oct; 58(12):2275-2288. PMID: 28986437
As the lipidomics field continues to advance, self-evaluation within the community is critical. Here, we performed an interlaboratory comparison exercise for lipidomics using Standard Reference Material (SRM) 1950-Metabolites in Frozen...
4.
Joseph G, Soler A, Hutcheson R, Hunter I, Bradford C, Hutcheson B, et al.
Am J Physiol Heart Circ Physiol . 2016 Dec; 312(3):H528-H540. PMID: 28011587
Coronary collateral growth (CCG) is impaired in metabolic syndrome (MetS). microRNA-145 (miR-145-Adv) delivery to our rat model of MetS (JCR) completely restored and neutrophil depletion significantly improved CCG. We determined...
5.
Chen L, Joseph G, Zhang F, Nguyen H, Jiang H, Gotlinger K, et al.
Vascul Pharmacol . 2016 Apr; 83:57-65. PMID: 27084395
Angiogenesis is an important adaptation for recovery from peripheral ischemia. Here, we determined whether 20-hydroxyeicosatetraenoic acid (20-HETE) contributes to ischemia-induced angiogenesis and assessed its underlying molecular and cellular mechanisms using...
6.
Chen L, Ackerman R, Saleh M, Gotlinger K, Kessler M, Mendelowitz L, et al.
J Pharmacol Exp Ther . 2014 Jan; 348(3):442-51. PMID: 24403517
Circulating endothelial progenitor cells (EPC) contribute to postnatal neovascularization. We identified the cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid (CYP4A/F-20-HETE) system as a novel regulator of EPC functions associated with angiogenesis in vitro....
7.
Fox T, Gotlinger K, Dunn M, Lee O, Milman T, Zaidman G, et al.
Cornea . 2013 Jun; 32(9):1276-82. PMID: 23792437
Purpose: Cyclooxygenase (COX)-, lipoxygenase (LOX)-, and cytochrome P450 monooxygenase (CYP)-derived eicosanoids have been implicated in ocular surface inflammation and neovascularization. These eicosanoids are subjected to regulation by enzymes, such as...
8.
Issan Y, Hochhauser E, Guo A, Gotlinger K, Kornowski R, Leshem-Lev D, et al.
Prostaglandins Other Lipid Mediat . 2013 Jan; 100-101:15-21. PMID: 23291334
Background: Circulating endothelial progenitor cells (EPCs) are recruited from the blood system to sites of ischemia and endothelial damage, where they contribute to the repair and development of blood vessels....
9.
Kummer N, Nowicki T, Azzi J, Reyes I, Iacob C, Xie S, et al.
J Cell Biochem . 2012 Jan; 113(6):1998-2008. PMID: 22253131
Arachidonate 5-lipoxygenase (ALOX5) expression and activity has been implicated in tumor pathogenesis, yet its role in papillary thyroid carcinoma (PTC) has not been characterized. ALOX5 protein and mRNA were upregulated...
10.
Sun P, Antoun J, Lin D, Yue P, Gotlinger K, Capdevila J, et al.
Hypertension . 2011 Dec; 59(2):339-47. PMID: 22184322
The aim of this study is to test whether the Cyp2c44 epoxygenase-dependent metabolism of arachidonic acid prevents the hypertensive effect of a high K (HK) intake by inhibiting the epithelial...