Katherine E Pinnick
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Explore the profile of Katherine E Pinnick including associated specialties, affiliations and a list of published articles.
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24
Citations
1113
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Recent Articles
11.
Hilton C, Neville M, Wittemans L, Todorcevic M, Pinnick K, Pulit S, et al.
EBioMedicine
. 2019 Jun;
44:467-475.
PMID: 31151930
Background: Abdominal fat mass is associated with metabolic risk whilst gluteal femoral fat is paradoxically protective. MicroRNAs are known to be necessary for adipose tissue formation and function but their...
12.
Neville M, Wittemans L, Pinnick K, Todorcevic M, Kaksonen R, Pietilainen K, et al.
PLoS One
. 2019 May;
14(5):e0217644.
PMID: 31145760
Waist-to-hip ratio (WHR) is a prominent cardiometabolic risk factor that increases cardio-metabolic disease risk independently of BMI and for which multiple genetic loci have been identified. However, WHR is a...
13.
Pinnick K, Hodson L
J Physiol
. 2019 Mar;
597(14):3527-3537.
PMID: 30883738
Excessive consumption of free sugars (which typically includes a composite of glucose and fructose) is associated with an increased risk of developing chronic metabolic diseases including obesity, non-alcoholic fatty liver...
14.
Pinnick K, Gunn P, Hodson L
Methods Mol Biol
. 2018 Oct;
1862:83-96.
PMID: 30315461
Stable isotopes are powerful tools for tracing the metabolic fate of molecules in the human body. In this chapter, we focus on the use of deuterium (H), a stable isotope...
15.
Denton N, Pinnick K, Karpe F
Mol Metab
. 2018 Aug;
16:172-179.
PMID: 30100245
Objective: The composition of the extracellular matrix (ECM) impacts adipocyte function and might determine adipose tissue (AT) function and distribution. Cartilage oligomeric matrix protein (COMP), a matricellular protein usually studied...
16.
Todorcevic M, Hilton C, McNeil C, Christodoulides C, Hodson L, Karpe F, et al.
Adipocyte
. 2017 Apr;
6(1):40-55.
PMID: 28452592
Upper-body adiposity is associated with increased metabolic disease risk, while lower-body adiposity is paradoxically protective. Efforts to understand the underlying mechanisms require appropriate and reproducible in vitro culture models. We...
17.
Hilton C, Karpe F, Pinnick K
Biochim Biophys Acta
. 2015 Feb;
1851(5):686-96.
PMID: 25668679
In this review we discuss the role of developmental transcription factors in adipose tissue biology with a focus on how these developmental genes may contribute to regional variation in adipose...
18.
Karpe F, Pinnick K
Nat Rev Endocrinol
. 2014 Nov;
11(2):90-100.
PMID: 25365922
The distribution of adipose tissue in the body has wide-ranging and reproducible associations with health and disease. Accumulation of adipose tissue in the upper body (abdominal obesity) is associated with...
19.
Bensaad K, Favaro E, Lewis C, Peck B, Lord S, Collins J, et al.
Cell Rep
. 2014 Sep;
9(1):349-365.
PMID: 25263561
An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of which are involved...
20.
Pinnick K, Nicholson G, Manolopoulos K, McQuaid S, Valet P, Frayn K, et al.
Diabetes
. 2014 Jun;
63(11):3785-97.
PMID: 24947352
Upper- and lower-body fat depots exhibit opposing associations with obesity-related metabolic disease. We defined the relationship between DEXA-quantified fat depots and diabetes/cardiovascular risk factors in a healthy population-based cohort (n...