Katharina Paschinger
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Explore the profile of Katharina Paschinger including associated specialties, affiliations and a list of published articles.
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1249
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Recent Articles
1.
Hykollari A, Malzl D, Jin C, Eschenbach C, Kianickova K, Wilson I, et al.
BBA Adv
. 2025 Feb;
7:100142.
PMID: 39911813
Dictyostelia are cellular slime molds, a group of Amoebozoa, that form multicellular fruiting bodies out of aggregating cells able of differentiating into resistant spore forms. In previous studies on ,...
2.
Kendler J, Wls F, Thapliyal S, Arcalis E, Gabriel H, Kubitschek S, et al.
J Biol Chem
. 2024 Oct;
300(12):107944.
PMID: 39481603
N-glycans with complex core chitobiose modifications are observed in various free-living and parasitic nematodes but are absent in mammals. Using Caenorhabditis elegans as a model, we demonstrated that the core...
3.
Dutkiewicz Z, Varrot A, Breese K, Stubbs K, Nuschy L, Adduci I, et al.
Biochemistry
. 2024 Jul;
63(15):1941-1954.
PMID: 39058279
Hexosaminidases are key enzymes in glycoconjugate metabolism and occur in all kingdoms of life. Here, we have investigated the phylogeny of the GH20 glycosyl hydrolase family in nematodes and identified...
4.
Paschinger K, Vanbeselaere J, Wilson I
Methods Mol Biol
. 2024 Feb;
2762:123-138.
PMID: 38315363
Glycoproteins result from post-translational modification of proteins by glycans attached to certain side chains, with possible heterogeneity due to different structures being possible at the same glycosylation site.In contrast to...
5.
Eckmair B, Gao C, Mehta A, Dutkiewicz Z, Vanbeselaere J, Cummings R, et al.
Mol Cell Proteomics
. 2024 Jan;
23(2):100711.
PMID: 38182041
Glycans are key to host-pathogen interactions, whereby recognition by the host and immunomodulation by the pathogen can be mediated by carbohydrate binding proteins, such as lectins of the innate immune...
6.
Eckmair B, Gao C, Mehta A, Dutkiewicz Z, Vanbeselaere J, Cummings R, et al.
bioRxiv
. 2023 Oct;
PMID: 37790353
Glycans are key to host-pathogen interactions, whereby recognition by the host and immunomodulation by the pathogen can be mediated by carbohydrate binding proteins, such as lectins of the innate immune...
7.
Paschinger K, Wols F, Yan S, Jin C, Vanbeselaere J, Dutkiewicz Z, et al.
J Biol Chem
. 2023 Feb;
299(4):103053.
PMID: 36813232
Simple organisms are often considered to have simple glycomes, but plentiful paucimannosidic and oligomannosidic glycans overshadow the less abundant N-glycans with highly variable core and antennal modifications; Caenorhabditis elegans is...
8.
Wilson I, Yan S, Jin C, Dutkiewicz Z, Rendic D, Palmberger D, et al.
Mol Cell Proteomics
. 2023 Jan;
22(3):100505.
PMID: 36717059
Caenorhabditis elegans is a frequently employed genetic model organism and has been the object of a wide range of developmental, genetic, proteomic, and glycomic studies. Here, using an off-line MALDI-TOF-MS...
9.
Hykollari A, Paschinger K, Wilson I
Mass Spectrom Rev
. 2021 May;
41(6):945-963.
PMID: 33955035
The approaches for analysis of N-glycans have radically altered in the last 20 years or so. Due to increased sensitivity, mass spectrometry has become the predominant method in modern glycomics....
10.
Mondragon-Shem K, Wongtrakul-Kish K, Kozak R, Yan S, Wilson I, Paschinger K, et al.
Sci Rep
. 2020 Aug;
10(1):12903.
PMID: 32737362
During Leishmania transmission sand flies inoculate parasites and saliva into the skin of vertebrates. Saliva has anti-haemostatic and anti-inflammatory activities that evolved to facilitate bloodfeeding, but also modulate the host's...