Katelyn Fenn
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Explore the profile of Katelyn Fenn including associated specialties, affiliations and a list of published articles.
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13
Citations
521
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Recent Articles
1.
Capewell P, Monk S, Ivens A, MacGregor P, Fenn K, Walrad P, et al.
PLoS One
. 2013 Jul;
8(6):e67069.
PMID: 23840587
The gene expression of Trypanosoma brucei has been examined extensively in the blood of mammalian hosts and in forms found in the midgut of its arthropod vector, the tsetse fly....
2.
Walrad P, Capewell P, Fenn K, Matthews K
Nucleic Acids Res
. 2011 Dec;
40(7):2869-83.
PMID: 22140102
Post-transcriptional gene regulation is essential to eukaryotic development. This is particularly emphasized in trypanosome parasites where genes are co-transcribed in polycistronic arrays but not necessarily co-regulated. The small CCCH protein,...
3.
Droll D, Archer S, Fenn K, Delhi P, Matthews K, Clayton C
FEBS Lett
. 2010 Feb;
584(6):1156-62.
PMID: 20153321
Proteins with Pumilio RNA binding domains (Puf proteins) are ubiquitous in eukaryotes. Some Puf proteins bind to the 3'-untranslated regions of mRNAs, acting to repress translation and promote degradation; others...
4.
Kabani S, Fenn K, Ross A, Ivens A, Smith T, Ghazal P, et al.
BMC Genomics
. 2009 Sep;
10:427.
PMID: 19747379
Background: Trypanosomes undergo extensive developmental changes during their complex life cycle. Crucial among these is the transition between slender and stumpy bloodstream forms and, thereafter, the differentiation from stumpy to...
5.
Fenn K, Matthews K
Curr Opin Microbiol
. 2007 Nov;
10(6):539-46.
PMID: 17997129
Developmental events in the life-cycle of the sleeping sickness parasite comprise integrated changes in cell morphology, metabolism, gene expression and signalling pathways. In each case these processes differ from the...
6.
Paterou A, Walrad P, Craddy P, Fenn K, Matthews K
J Biol Chem
. 2006 Oct;
281(51):39002-13.
PMID: 17043361
The post-transcriptional control of gene expression is becoming increasingly important in the understanding of regulated events in eukaryotic cells. The parasitic kinetoplastids have a unique reliance on such processes, because...
7.
Fenn K, Conlon C, Jones M, Quail M, Holroyd N, Parkhill J, et al.
PLoS Pathog
. 2006 Oct;
2(10):e94.
PMID: 17040125
Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of mutualism....
8.
Mayho M, Fenn K, Craddy P, Crosthwaite S, Matthews K
Nucleic Acids Res
. 2006 Oct;
34(18):5312-24.
PMID: 17012283
Trypanosomes represent an excellent model for the post-transcriptional regulation of gene expression because their genome is organized into polycistronic transcription units. However, few signals governing developmental stage-specific expression have been...
9.
Fenn K, Blaxter M
Trends Ecol Evol
. 2006 May;
19(4):163-6.
PMID: 16701248
The intracellular symbiotic bacteria of filarial nematodes have inspired new ideas for the control of disease using antibacterial drugs. For effective, long-term control, this requires that the bacteria are essential...
10.
Fenn K, Blaxter M
Trends Parasitol
. 2006 Jan;
22(2):60-5.
PMID: 16406333
Wolbachia bacteria are endosymbiotic partners of many animal species, in which they behave as either parasites (in arthropod hosts) or mutualists (in nematode hosts). What biochemistry and biology underpin these...