Kate M Candelario
Overview
Explore the profile of Kate M Candelario including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
195
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0
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Recent Articles
1.
Yang C, Trivedi V, Dyson K, Gu T, Candelario K, Yegorov O, et al.
Genome Med
. 2024 Aug;
16(1):102.
PMID: 39160595
Background: The current standard of care treatments for medulloblastoma are insufficient as these do not take tumor heterogeneity into account. Newer, safer, patient-specific treatment approaches are required to treat high-risk...
2.
Ogando-Rivas E, Castillo P, Yang C, Trivedi V, Zhang D, Pohl-Guimaraes F, et al.
Mol Ther Methods Clin Dev
. 2024 Feb;
32(1):101192.
PMID: 38327807
The COVID-19 pandemic has caused about seven million deaths worldwide. Preventative vaccines have been developed including Spike gp mRNA-based vaccines that provide protection to immunocompetent patients. However, patients with primary...
3.
Ogando-Rivas E, Castillo P, Jones N, Trivedi V, Drake J, Dechkovskaia A, et al.
Microbiol Immunol
. 2022 Feb;
66(5):201-211.
PMID: 35150167
Adoptive T-cell therapies have been successfully used as prophylaxis or treatment for immunocompromised patients at risk of viral infections or advanced cancers. Unfortunately, for some refractory cancers, they have failed....
4.
Hwang E, Sayour E, Flores C, Grant G, Wechsler-Reya R, Hoang-Minh L, et al.
Nat Cancer
. 2022 Feb;
3(1):11-24.
PMID: 35121998
Pediatric central nervous system tumors are the most common solid malignancies in childhood, and aggressive therapy often leads to long-term sequelae in survivors, making these tumors challenging to treat. Immunotherapy...
5.
Candelario K, Balaj L, Zheng T, Skog J, Scheffler B, Breakefield X, et al.
J Comp Neurol
. 2019 Nov;
528(7):1203-1215.
PMID: 31743443
Extracellular vesicles, including exosomes/microvesicles (EMVs), have been described as sensitive biomarkers that represent disease states and response to therapies. In light of recent reports of disease-mirroring EMV molecular signatures, the...
6.
Li L, Candelario K, Thomas K, Wang R, Wright K, Messier A, et al.
J Neurosci
. 2014 Dec;
34(50):16713-9.
PMID: 25505323
HIF-1α is a hypoxia-inducible protein that regulates many cell and molecular processes, including those involved in angiogenesis and stem cell maintenance. Prior studies demonstrated constitutive HIF-1α stabilization in neural stem...
7.
Candelario K, Steindler D
Trends Mol Med
. 2014 May;
20(7):368-74.
PMID: 24835084
Extracellular vesicles (EVs) are released from many cell types, including normal and pathological cells, and range from 30 to 1000 nm in size. Once thought to be a mechanism for...
8.
Felsenstein K, Candelario K, Steindler D, Borchelt D
Transl Res
. 2013 Nov;
163(4):432-8.
PMID: 24286919
Identifying novel, effective therapeutics for Alzheimer's disease (AD) is one of the major unmet medical needs for the coming decade. Because the current paradigm for developing and testing disease-modifying AD...
9.
Candelario K, Shuttleworth C, Cunningham L
J Neurochem
. 2013 Feb;
125(3):420-9.
PMID: 23410250
Neural stem/progenitor cells (NSPCs) are multipotent cells within the embryonic and adult brain that give rise to both neuronal and glial cell lineages. Maintenance of NSPC multipotency is promoted by...