Paul Castillo
Overview
Explore the profile of Paul Castillo including associated specialties, affiliations and a list of published articles.
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Articles
51
Citations
571
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Recent Articles
1.
Alperstein W, Lee J, Chellapandian D, Booth N, Galvez-Silva J, Joyce M, et al.
Pediatr Transplant
. 2025 Mar;
29(3):e70059.
PMID: 40045826
Background: Florida Pediatric Bone Marrow Transplant and Cell Therapy Consortium (FPBCC) was formed in 2018 by five pediatric transplant programs in Florida. The key objectives of the consortium are to...
2.
Lynch E, Citta A, Alford C, Ligon J, Dalal M, Castillo P, et al.
Leuk Res Rep
. 2024 Aug;
22:100472.
PMID: 39175509
Patients who receive allogeneic hematopoietic stem cell transplantation (alloHSCT) are at risk for developing persistent thrombocytopenia. Here, we describe treatment with avatrombopag, a thrombopoietin receptor agonist, in a pediatric patient...
3.
Zinter M, Dvorak C, Mayday M, Reyes G, Simon M, Pearce E, et al.
Nat Med
. 2024 May;
30(7):1982-1993.
PMID: 38783139
Hematopoietic cell transplantation (HCT) uses cytotoxic chemotherapy and/or radiation followed by intravenous infusion of stem cells to cure malignancies, bone marrow failure and inborn errors of immunity, hemoglobin and metabolism....
4.
Kashif R, Horn B, Milner J, Joyce M, Dalal M, Lee J, et al.
Pediatr Transplant
. 2024 May;
28(4):e14784.
PMID: 38766976
Background: The goal of this study was to assess the effect of donor type and pre-transplant immunotherapy (IST) on outcomes of hematopoietic stem cell transplantation (HSCT) for children and young...
5.
Shimano K, Sasa G, Broglie L, Gloude N, Myers K, Nakano T, et al.
Pediatr Blood Cancer
. 2024 May;
71(8):e31075.
PMID: 38764170
Severe aplastic anemia (SAA) is a rare potentially fatal hematologic disorder. Although overall outcomes with treatment are excellent, there are variations in management approach, including differences in treatment between adult...
6.
Shimano K, Rothman J, Allen S, Castillo P, de Jong J, Dror Y, et al.
Pediatr Blood Cancer
. 2024 May;
71(8):e31070.
PMID: 38757488
Severe aplastic anemia (SAA) is a rare potentially fatal hematologic disorder. Although overall outcomes with treatment are excellent, there are variations in management approach, including differences in treatment between adult...
7.
Mendez-Gomez H, DeVries A, Castillo P, von Roemeling C, Qdaisat S, Stover B, et al.
Cell
. 2024 May;
187(10):2521-2535.e21.
PMID: 38697107
Cancer immunotherapy remains limited by poor antigenicity and a regulatory tumor microenvironment (TME). Here, we create "onion-like" multi-lamellar RNA lipid particle aggregates (LPAs) to substantially enhance the payload packaging and...
8.
Ogando-Rivas E, Castillo P, Yang C, Trivedi V, Zhang D, Pohl-Guimaraes F, et al.
Mol Ther Methods Clin Dev
. 2024 Feb;
32(1):101192.
PMID: 38327807
The COVID-19 pandemic has caused about seven million deaths worldwide. Preventative vaccines have been developed including Spike gp mRNA-based vaccines that provide protection to immunocompetent patients. However, patients with primary...
9.
Trivedi V, Yang C, Klippel K, Yegorov O, von Roemeling C, Hoang-Minh L, et al.
Genome Med
. 2024 Jan;
16(1):17.
PMID: 38268001
Background: Despite advancements in the successful use of immunotherapy in treating a variety of solid tumors, applications in treating brain tumors have lagged considerably. This is due, at least in...
10.
Gera K, Chauhan A, Castillo P, Rahman M, Mathavan A, Mathavan A, et al.
J Hematol Oncol
. 2024 Jan;
17(1):4.
PMID: 38191498
Myelodysplastic neoplasms (MDS) define clonal hematopoietic malignancies characterized by heterogeneous mutational and clinical spectra typically seen in the elderly. Curative treatment entails allogeneic hematopoietic stem cell transplant, which is often...