Karolin H Nord
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Explore the profile of Karolin H Nord including associated specialties, affiliations and a list of published articles.
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36
Citations
732
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Recent Articles
1.
Saba K, Difilippo V, Styring E, Nilsson J, Magnusson L, van den Bos H, et al.
NPJ Genom Med
. 2024 Sep;
9(1):42.
PMID: 39322633
Amplification of the MDM2 and CDK4 genes on chromosome 12 is commonly associated with low-grade osteosarcomas. In this study, we conducted high-resolution genomic and transcriptomic analyses on 33 samples from...
2.
Saba K, Difilippo V, Kovac M, Cornmark L, Magnusson L, Nilsson J, et al.
J Pathol
. 2023 Nov;
262(2):147-160.
PMID: 38010733
TP53 is the most frequently mutated gene in human cancer. This gene shows not only loss-of-function mutations but also recurrent missense mutations with gain-of-function activity. We have studied the primary...
3.
Difilippo V, Saba K, Styring E, Magnusson L, Nilsson J, Nathrath M, et al.
Lab Invest
. 2023 Nov;
104(1):100283.
PMID: 37931683
Osteosarcoma is the most common primary bone malignancy, often detected in children and adolescents and commonly associated with TP53 alterations along with a high number of chromosomal rearrangements. However, osteosarcoma...
4.
Kao Y, Yoshida A, Hsieh T, Nord K, Saba K, Ichikawa H, et al.
Mod Pathol
. 2023 Feb;
36(2):100011.
PMID: 36853784
Bizarre parosteal osteochondromatous proliferation (BPOP) (Nora lesion) is a benign bone surface lesion, which most commonly occurs in the digits of young patients and has a high rate of recurrence....
5.
Andersson N, Saba K, Magnusson L, Nilsson J, Karlsson J, Nord K, et al.
Genes Chromosomes Cancer
. 2022 Sep;
62(2):93-100.
PMID: 36124964
Chromosomal instability is a common feature in malignant tumors. Previous studies have indicated that inactivation of the classical tumor suppressor genes RB1, CDKN2A, and TP53 may contribute to chromosomal aberrations...
6.
Ameline B, Nathrath M, Nord K, de Flon F, Bovee J, Krieg A, et al.
Mod Pathol
. 2022 Mar;
35(9):1204-1211.
PMID: 35347251
Rearrangements of the transcription factors FOS and FOSB have recently been identified as the genetic driver event underlying osteoid osteoma and osteoblastoma. Nuclear overexpression of FOS and FOSB have since...
7.
Saba K, Cornmark L, Hofvander J, Magnusson L, Nilsson J, van den Bos H, et al.
J Pathol Clin Res
. 2020 Jun;
6(4):231-237.
PMID: 32542935
Osteoblastoma is a locally aggressive tumour of bone. Until recently, its underlying genetic features were largely unknown. During the past two years, reports have demonstrated that acquired structural variations affect...
8.
Yang M, Safavi S, Woodward E, Duployez N, Olsson-Arvidsson L, Ungerback J, et al.
Blood
. 2020 May;
136(8):946-956.
PMID: 32384149
Mutations in the FMS-like tyrosine kinase 3 (FLT3) gene in 13q12.2 are among the most common driver events in acute leukemia, leading to increased cell proliferation and survival through activation...
9.
Ameline B, Saba K, Kovac M, Magnusson L, Witt O, Bielack S, et al.
J Pathol Clin Res
. 2020 Feb;
6(2):107-112.
PMID: 32022484
Neurotrophic tyrosine receptor kinase (NTRK) fusions are promising molecular targets that have been described in a broad range of malignant tumours. Fusions commonly lead to the expression of chimeric proteins...
10.
Saba K, Cornmark L, Rissler M, Fioretos T, Astrom K, Haglund F, et al.
Genes Chromosomes Cancer
. 2019 May;
58(10):731-736.
PMID: 31066955
Conventional osteosarcoma is the most common primary malignancy of bone. This group of neoplasms is subclassified according to specific histological features, but hitherto there has been no correlation between subtype,...