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Karolin Guldevall

Explore the profile of Karolin Guldevall including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 386
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Recent Articles
1.
Sandstrom N, Brandt L, Sandoz P, Zambarda C, Guldevall K, Schulz-Ruhtenberg M, et al.
Lab Chip . 2022 Apr; 22(11):2107-2121. PMID: 35470832
Miniaturization of cell culture substrates enables controlled analysis of living cells in confined micro-scale environments. This is particularly suitable for imaging individual cells over time, as they can be monitored...
2.
Walwyn-Brown K, Guldevall K, Saeed M, Pende D, Onfelt B, MacDonald A, et al.
J Immunol . 2018 Aug; 201(7):2028-2041. PMID: 30120122
Cross-talk between NK cells and dendritic cells (DCs) is important in Th1 immune responses, including antitumor immunity and responses to infections. DCs also play a crucial role in polarizing Th2...
3.
Srpan K, Ambrose A, Karampatzakis A, Saeed M, Cartwright A, Guldevall K, et al.
J Cell Biol . 2018 Jul; 217(9):3267-3283. PMID: 29967280
Natural Killer (NK) cells can engage multiple virally infected or tumor cells sequentially and deliver perforin for cytolytic killing of these targets. Using microscopy to visualize degranulation from individual NK...
4.
Sarhan D, Brandt L, Felices M, Guldevall K, Lenvik T, Hinderlie P, et al.
Blood Adv . 2018 Jun; 2(12):1459-1469. PMID: 29941459
Myelodysplastic syndrome (MDS) is a clonal heterogeneous stem cell disorder driven by multiple genetic and epigenetic alterations resulting in ineffective hematopoiesis. MDS has a high frequency of immune suppressors, including...
5.
Vanherberghen B, Frisk T, Forslund E, Olofsson P, Guldevall K, Onfelt B
Methods Mol Biol . 2016 May; 1441:87-106. PMID: 27177659
NK cell heterogeneity has primarily been studied either on the population level, measuring average responses, or on the single cell level by flow cytometry, providing static snapshots. These approaches have...
6.
Guldevall K, Brandt L, Forslund E, Olofsson K, Frisk T, Olofsson P, et al.
Front Immunol . 2016 Apr; 7:119. PMID: 27092139
Here, we report a screening platform for assessment of the cytotoxic potential of individual natural killer (NK) cells within larger populations. Human primary NK cells were distributed across a silicon-glass...
7.
Vanherberghen B, Olofsson P, Forslund E, Sternberg-Simon M, Khorshidi M, Pacouret S, et al.
Blood . 2013 Jan; 121(8):1326-34. PMID: 23287857
Despite intense scrutiny of the molecular interactions between natural killer (NK) and target cells, few studies have been devoted to dissection of the basic functional heterogeneity in individual NK cell...
8.
Wilkinson K, Ekstrand-Hammarstrom B, Ahlinder L, Guldevall K, Pazik R, Kepinski L, et al.
Nanoscale . 2012 Oct; 4(23):7383-93. PMID: 23070150
Nanoparticles of iron oxide generated by wearing of vehicles have been modelled with a tailored solution of size-uniform engineered magnetite particles produced by the Bradley reaction, a solvothermal metal-organic approach...
9.
Forslund E, Guldevall K, Olofsson P, Frisk T, Christakou A, Wiklund M, et al.
Front Immunol . 2012 Oct; 3:300. PMID: 23060879
Each individual has a heterogeneous pool of NK cells consisting of cells that may be specialized towards specific functional responses such as secretion of cytokines or killing of tumor cells....
10.
Frisk T, Khorshidi M, Guldevall K, Vanherberghen B, Onfelt B
Biomed Microdevices . 2011 Apr; 13(4):683-93. PMID: 21465090
We present a novel microwell array platform suited for various cell-imaging assays where single cell resolution is important. The platform consists of an exchangeable silicon-glass microchip for cell biological applications...