Karl J A McCullagh
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Explore the profile of Karl J A McCullagh including associated specialties, affiliations and a list of published articles.
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11
Citations
226
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Recent Articles
1.
Kennedy D, Wheatley A, McCullagh K
Biomedicines
. 2022 Jul;
10(8).
PMID: 35892681
Angiogenesis is the formation of new blood vessels from pre-existing vessels. Adequate oxygen transport and waste removal are necessary for tissue homeostasis. Restrictions in blood supply can lead to ischaemia...
2.
Kennedy D, Coen B, Wheatley A, McCullagh K
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008876
The chick chorioallantoic membrane (CAM) assay model of angiogenesis has been highlighted as a relatively quick, low cost and effective model for the study of pro-angiogenic and anti-angiogenic factors. The...
3.
Marsico G, Jin C, Abbah S, Brauchle E, Thomas D, Rebelo A, et al.
Biomaterials
. 2021 Jan;
269:120641.
PMID: 33493768
Critical limb ischemia (CLI) is characterized by the impairment of microcirculation, necrosis and inflammation of the muscular tissue. Although the role of glycans in mediating inflammation has been reported, changes...
4.
Bahri O, Naldaiz-Gastesi N, Kennedy D, Wheatley A, Izeta A, McCullagh K
Sci Rep
. 2019 Nov;
9(1):15964.
PMID: 31685850
The dermal striated muscle panniculus carnosus (PC), prevalent in lower mammals with remnants in humans, is highly regenerative, and whose function is purported to be linked to defence and shivering...
5.
Naldaiz-Gastesi N, Bahri O, de Munain A, McCullagh K, Izeta A
J Anat
. 2018 Jun;
PMID: 29893024
The panniculus carnosus is a thin striated muscular layer intimately attached to the skin and fascia of most mammals, where it provides skin twitching and contraction functions. In humans, the...
6.
McCullagh K, Perlingeiro R
Adv Drug Deliv Rev
. 2014 Jul;
84:198-207.
PMID: 25049085
Skeletal muscle has a tremendous ability to regenerate, attributed to a well-defined population of muscle stem cells called satellite cells. However, this ability to regenerate diminishes with age and can...
7.
McCullagh K
Stem Cell Res Ther
. 2012 May;
3(3):19.
PMID: 22643017
Ageing is a biological certainty for all living organisms, and is due to the loss of tissue homeostasis and regenerative capacity (except for newts) in which somatic stem cells are...
8.
Clarke W, Edwards B, McCullagh K, Kemp M, Moorwood C, Sherman D, et al.
J Cell Sci
. 2010 Jul;
123(Pt 15):2543-52.
PMID: 20587592
Syncoilin is an atypical type III intermediate filament (IF) protein, which is expressed in muscle and is associated with the dystrophin-associated protein complex. Here, we show that syncoilin is expressed...
9.
McCullagh K, Edwards B, Kemp M, Giles L, Burgess M, Davies K
Mamm Genome
. 2008 Jul;
19(5):339-51.
PMID: 18594912
Syncoilin is a 64-kDa intermediate filament protein expressed in skeletal muscle and enriched at the perinucleus, sarcolemma, and myotendinous and neuromuscular junctions. Due to its pattern of cellular localization and...
10.
McCullagh K, Edwards B, Poon E, Lovering R, Paulin D, Davies K
Neuromuscul Disord
. 2007 Jul;
17(11-12):970-9.
PMID: 17629480
The intermediate filament-like protein syncoilin is a member of the dystrophin protein complex, and links the complex to the cytoskeleton through binding alpha-dystrobrevin and desmin in muscle. Here, we identify...