Karl E Duderstadt
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Explore the profile of Karl E Duderstadt including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
795
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Recent Articles
1.
Karl L, Galanti L, Bantele S, Metzner F, Safaric B, Rajappa L, et al.
Life Sci Alliance
. 2023 Jul;
6(9).
PMID: 37468166
Fun30 is the prototype of the Fun30-SMARCAD1-ETL subfamily of nucleosome remodelers involved in DNA repair and gene silencing. These proteins appear to act as single-subunit nucleosome remodelers, but their molecular...
2.
Huisjes N, Retzer T, Scherr M, Agarwal R, Rajappa L, Safaric B, et al.
Elife
. 2022 Sep;
11.
PMID: 36098381
The rapid development of new imaging approaches is generating larger and more complex datasets, revealing the time evolution of individual cells and biomolecules. Single-molecule techniques, in particular, provide access to...
3.
Dequeker B, Scherr M, Brandao H, Gassler J, Powell S, Gaspar I, et al.
Nature
. 2022 May;
606(7912):197-203.
PMID: 35585235
Eukaryotic genomes are compacted into loops and topologically associating domains (TADs), which contribute to transcription, recombination and genomic stability. Cohesin extrudes DNA into loops that are thought to lengthen until...
4.
Scherr M, Wahab S, Remus D, Duderstadt K
Cell Rep
. 2022 Mar;
38(12):110531.
PMID: 35320708
Fundamental to our understanding of chromosome duplication is the idea that replication origins function both as sites where MCM helicases are loaded during the G1 phase and where synthesis begins...
5.
Safaric B, Chacin E, Scherr M, Rajappa L, Gebhardt C, Kurat C, et al.
Nucleic Acids Res
. 2022 Jan;
50(3):1317-1334.
PMID: 35061899
Chromosome replication depends on efficient removal of nucleosomes by accessory factors to ensure rapid access to genomic information. Here, we show this process requires recruitment of the nucleosome reorganization activity...
6.
Urbanska M, Ludecke A, Walter W, van Oijen A, Duderstadt K, Diez S
Small
. 2021 Mar;
17(18):e2007388.
PMID: 33759372
Cytoskeletal motors transform chemical energy into mechanical work to drive essential cellular functions. Optical trapping experiments have provided crucial insights into the operation of these molecular machines under load. However,...
7.
Bauernfried S, Scherr M, Pichlmair A, Duderstadt K, Hornung V
Science
. 2020 Nov;
371(6528).
PMID: 33243852
Inflammasomes function as intracellular sensors of pathogen infection or cellular perturbation and thereby play a central role in numerous diseases. Given the high abundance of NLRP1 in epithelial barrier tissues,...
8.
Agarwal R, Duderstadt K
Nat Commun
. 2020 Sep;
11(1):4714.
PMID: 32948754
The application of forces and torques on the single molecule level has transformed our understanding of the dynamic properties of biomolecules, but rare intermediates have remained difficult to characterize due...
9.
van Oijen A, Duderstadt K, Xiao J, Fishel R
J Mol Biol
. 2018 Aug;
430(22):4441-4442.
PMID: 30102893
No abstract available.
10.
Hill F, van Oijen A, Duderstadt K
J Chem Phys
. 2018 Apr;
148(12):123317.
PMID: 29604840
Single-molecule approaches present a powerful way to obtain detailed kinetic information at the molecular level. However, the identification of small rate changes is often hindered by the considerable noise present...