Karl Clark
Overview
Explore the profile of Karl Clark including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
110
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0
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Recent Articles
1.
Becker N, Peters J, Lewis E, Daby C, Clark K, Maher 3rd L
Nucleic Acids Res
. 2024 Jul;
52(16):9996-10004.
PMID: 39077947
Natural prokaryotic gene repression systems often exploit DNA looping to increase the local concentration of gene repressor proteins at a regulated promoter via contributions from repressor proteins bound at distant...
2.
Lee H, Shams S, Dang Thi V, Boyum G, Modhurima R, Hall E, et al.
Res Sq
. 2023 Sep;
PMID: 37720015
The vertebrate stress response (SR) is mediated by the hypothalamic-pituitary-adrenal (HPA) axis and contributes to generating context appropriate physiological and behavioral changes. Although the HPA axis plays vital roles both...
3.
Tepe B, Macke E, Niceta M, Hubshman M, Kanca O, Schultz-Rogers L, et al.
Am J Hum Genet
. 2023 Apr;
110(5):774-789.
PMID: 37054711
The Integrator complex is a multi-subunit protein complex that regulates the processing of nascent RNAs transcribed by RNA polymerase II (RNAPII), including small nuclear RNAs, enhancer RNAs, telomeric RNAs, viral...
4.
Kim J, Clark K, Barton C, Tanguay R, Moulton H
Methods Mol Biol
. 2018 Sep;
1828:293-306.
PMID: 30171549
Morpholino oligomers have great therapeutic potential for treatment of a broad range of human diseases, including viral, bacterial, age-related, and genetic diseases, but they suffer from poor systemic delivery into...
5.
Madeo M, Stewart M, Sun Y, Sahir N, Wiethoff S, Chandrasekar I, et al.
Am J Hum Genet
. 2016 May;
98(6):1249-1255.
PMID: 27236917
Glutamatergic neurotransmission governs excitatory signaling in the mammalian brain, and abnormalities of glutamate signaling have been shown to contribute to both epilepsy and hyperkinetic movement disorders. The etiology of many...
6.
Dupuy A, Clark K, Carlson C, Fritz S, Davidson A, Markley K, et al.
Proc Natl Acad Sci U S A
. 2002 Mar;
99(7):4495-9.
PMID: 11904379
Transposons have been used in invertebrates for transgenesis and insertional mutagens in genetic screens. We tested a functional transposon called Sleeping Beauty in the one-cell mouse embryo. In this report,...