Karishma Randhave
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Explore the profile of Karishma Randhave including associated specialties, affiliations and a list of published articles.
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3
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1
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Recent Articles
1.
DeLeeuw M, Shen W, Tian X, Ding C, Randhave K, Kang J
Epilepsy Res
. 2025 Feb;
210:107514.
PMID: 39923323
Background: Haploinsufficient deletions of GABA transporter 1 (GAT-1)- encoding SLC6A1, and GABA transporter 3 (GAT-3)-encoding SLC6A11 are implicated in epileptic syndromes. Despite their significance, the impact of these deletions has...
2.
Poliquin S, Nwosu G, Randhave K, Shen W, Flamm C, Kang J
Int J Mol Sci
. 2024 May;
25(9).
PMID: 38731820
A significant number of patients with genetic epilepsy do not obtain seizure freedom, despite developments in new antiseizure drugs, suggesting a need for novel therapeutic approaches. Many genetic epilepsies are...
3.
Shen W, Flamm C, Delahanty A, Casteel E, Biven M, DeLeeuw M, et al.
Epilepsia
. 2023 Sep;
65(1):204-217.
PMID: 37746768
Objective: γ-Aminobutyric acid type A (GABA ) receptor subunit gene mutations are major causes of various epilepsy syndromes, including severe kinds such as Dravet syndrome. Although the GABA receptor is...
4.
Nwosu G, Shen W, Zavalin K, Poliquin S, Randhave K, Flamm C, et al.
Int J Mol Sci
. 2023 May;
24(9).
PMID: 37176165
Lennox-Gastaut Syndrome (LGS) is a developmental and epileptic encephalopathy (DEE) characterized by multiple seizure types, electroencephalogram (EEG) patterns, and cognitive decline. Its etiology has a prominent genetic component, including variants...