Karin Fritz-Wolf
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Explore the profile of Karin Fritz-Wolf including associated specialties, affiliations and a list of published articles.
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30
Citations
462
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Recent Articles
1.
Dillenberger M, Werner A, Velten A, Rahlfs S, Becker K, Fritz-Wolf K
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628920
The protozoan parasite is the causative pathogen of the most severe form of malaria, for which novel strategies for treatment are urgently required. The primary energy supply for intraerythrocytic stages...
2.
Berneburg I, Stumpf M, Velten A, Rahlfs S, Przyborski J, Becker K, et al.
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37239962
As unicellular parasites are highly dependent on NADPH as a source for reducing equivalents, the main NADPH-producing enzymes glucose 6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD) of the pentose phosphate...
3.
Berneburg I, Rahlfs S, Becker K, Fritz-Wolf K
Commun Biol
. 2022 Dec;
5(1):1353.
PMID: 36494598
Since unicellular parasites highly depend on NADPH as a source for reducing equivalents, the pentose phosphate pathway, especially the first and rate-limiting NADPH-producing enzyme glucose 6-phosphate dehydrogenase (G6PD), is considered...
4.
Dillenberger M, Rahlfs S, Becker K, Fritz-Wolf K
Structure
. 2022 Aug;
30(10):1452-1461.e3.
PMID: 35998635
The protozoan parasite Plasmodium falciparum causes the most severe form of malaria and is highly dependent on glycolysis. Glycolytic enzymes were shown to be massively redox regulated, inter alia via...
5.
Fritz-Wolf K, Bathke J, Rahlfs S, Becker K
Curr Res Struct Biol
. 2022 Apr;
4:87-95.
PMID: 35434650
Plasmoredoxin is a 22 kDa thiol-disulfide oxidoreductase involved in cellular redox regulatory processes and antioxidant defense. The 1.6 Å structure of the protein, solved via X-ray crystallography, adopts a modified...
6.
Heimsch K, Gertzen C, Schuh A, Nietzel T, Rahlfs S, Przyborski J, et al.
Antioxid Redox Signal
. 2022 Jan;
37(1-3):1-18.
PMID: 35072524
Genetically encoded green fluorescent protein (GFP)-based redox biosensors are widely used to monitor specific and dynamic redox processes in living cells. Over the last few years, various biosensors for a...
7.
Meinohl C, Barnard S, Fritz-Wolf K, Unger M, Porr A, Heipel M, et al.
Cancers (Basel)
. 2019 Dec;
12(1).
PMID: 31861875
K-Ras is the most prominent driver of oncogenesis and no effective K-Ras inhibitors have been established despite decades of intensive research. Identifying new K-Ras-binding proteins and their interaction domains offers...
8.
Walter L, Surth V, Rottgerding F, Zipfel P, Fritz-Wolf K, Kraiczy P
Front Immunol
. 2019 Dec;
10:2722.
PMID: 31849943
sp. nov. has recently been reported as a novel human pathogenic spirochete causing Lyme disease (LD) in North America. Previous data reveal a higher spirochaetemia in the blood compared to...
9.
Weber A, Dam S, Saul V, Kuznetsova I, Muller C, Fritz-Wolf K, et al.
J Virol
. 2019 Apr;
93(13).
PMID: 30996098
Influenza A viruses (IAVs) quickly adapt to new environments and are well known to cross species barriers. To reveal a molecular basis for these phenomena, we compared the Ser/Thr and...
10.
Haeussler K, Fritz-Wolf K, Reichmann M, Rahlfs S, Becker K
J Mol Biol
. 2018 Aug;
430(21):4049-4067.
PMID: 30098336
The enzyme 6-phosphogluconate dehydrogenase (6PGD) of the malaria parasite Plasmodium falciparum catalyzes the third step of the pentose phosphate pathway converting 6-phosphogluconate (6PG) to ribulose 5-phosphate. The NADPH produced by...