Karen Laky
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Explore the profile of Karen Laky including associated specialties, affiliations and a list of published articles.
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25
Citations
360
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Recent Articles
1.
Laky K, Frischmeyer-Guerrerio P
J Allergy Clin Immunol
. 2024 Jun;
153(6):1485-1499.
PMID: 38849184
Eosinophilic esophagitis (EoE) is a disorder characterized by dysfunction and chronic local inflammation of the esophagus. The incidence and prevalence of EoE are increasing worldwide. The mechanisms responsible are poorly...
2.
Khalid M, Zektser E, Chu E, Li M, Utoh J, Ryan P, et al.
J Allergy Clin Immunol
. 2024 Mar;
153(6):1634-1646.
PMID: 38460680
Background: Systemic allergic reactions (sARs) following coronavirus disease 2019 (COVID-19) mRNA vaccines were initially reported at a higher rate than after traditional vaccines. Objective: We aimed to evaluate the safety...
3.
Haque T, Weissler K, Schmiechen Z, Laky K, Schwartz D, Li J, et al.
Sci Immunol
. 2024 Jan;
9(91):eadg8691.
PMID: 38241399
Allergic diseases are common, affecting more than 20% of the population. Genetic variants in the TGFβ pathway are strongly associated with atopy. To interrogate the mechanisms underlying this association, we...
4.
Shen Z, Robert L, Stolpman M, Che Y, Allen K, Saffery R, et al.
Genome Biol
. 2023 Nov;
24(1):252.
PMID: 37946302
Background: Metagenome-assembled genomes have greatly expanded the reference genomes for skin microbiome. However, the current reference genomes are largely based on samples from adults in North America and lack representation...
5.
Shen Z, Robert L, Stolpman M, Che Y, Walsh A, Saffery R, et al.
bioRxiv
. 2023 Jul;
PMID: 37398010
Metagenome-assembled genomes have greatly expanded the reference genomes for skin microbiome. However, the current reference genomes are largely based on samples from adults in North America and lack representation from...
6.
Laky K, Kinard J, Li J, Moore I, Lack J, Fischer E, et al.
Sci Immunol
. 2023 Jan;
8(79):eabp9940.
PMID: 36608150
Allergic diseases are a global health challenge. Individuals harboring loss-of-function variants in transforming growth factor-β receptor (TGFβR) genes have an increased prevalence of allergic disorders, including eosinophilic esophagitis. Allergic diseases...
7.
Abdi K, Laky K, Abshari M, Hill E, Lantz L, Singh N, et al.
Eur J Immunol
. 2022 Jul;
52(9):1431-1440.
PMID: 35816444
It is commonly believed that IL-12 produced by DCs in response to pathogens is the first signal that stimulates the production of IFN-γ by NK cells. However, IL-12 production by...
8.
Olivera A, Laky K, Hogan S, Frischmeyer-Guerrerio P
Front Immunol
. 2021 Jun;
12:709991.
PMID: 34177970
No abstract available.
9.
Abdi K, Thomas L, Laky K, Abshari M, Matzinger P, Long E
Immunohorizons
. 2020 Jul;
4(7):415-419.
PMID: 32665300
Dendritic cells (DCs) play a key role in the initiation of an immune response and are known as "professional" APCs because of their ability to activate naive T cells. A...
10.
Percopo C, Ma M, Brenner T, Krumholz J, Break T, Laky K, et al.
J Immunol
. 2018 Dec;
202(3):871-882.
PMID: 30578308
Severe respiratory virus infections feature robust local host responses that contribute to disease severity. Immunomodulatory strategies that limit virus-induced inflammation may be of critical importance, notably in the absence of...