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Karen H Watanabe

Explore the profile of Karen H Watanabe including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 360
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Recent Articles
1.
Dietrich S, Ma W, Ding Y, Watanabe K, Zelinski M, Sluka J
IEEE/ACM Trans Comput Biol Bioinform . 2024 Jul; 21(6):2598-2603. PMID: 38995706
The goal of the Multispecies Ovary Tissue Histology Electronic Repository (MOTHER) project is to establish a collection of nonhuman ovary histology images for multiple species as a resource for researchers...
2.
Watanabe K, Dietrich S, Ding Y, Ma W, Sluka J, Zelinski M
Biol Reprod . 2024 Jun; 111(3):512-515. PMID: 38900906
The Multispecies Ovary Tissue Histology Electronic Repository (MOTHER) is a publicly accessible repository of ovary histology images. MOTHER includes hundreds of images from nonhuman primates, as well as ovary histology...
3.
Morshead M, Jensen K, Ankley G, Vliet S, LaLone C, Aller A, et al.
Aquat Toxicol . 2023 Jun; 261:106607. PMID: 37354817
Several adverse outcome pathways (AOPs) have linked molecular initiating events like aromatase inhibition, androgen receptor (AR) agonism, and estrogen receptor (ER) antagonism to reproductive impairment in adult fish. Estrogen receptor...
4.
Villeneuve D, Blackwell B, Blanksma C, Cavallin J, Cheng W, Conolly R, et al.
Environ Toxicol Chem . 2022 Oct; 42(1):100-116. PMID: 36282016
To reduce the use of intact animals for chemical safety testing, while ensuring protection of ecosystems and human health, there is a demand for new approach methodologies (NAMs) that provide...
5.
Sinitsyn D, Garcia-Reyero N, Watanabe K
Front Toxicol . 2022 Apr; 4:838729. PMID: 35434701
Adverse outcome pathways (AOPs) include a sequence of events that connect a molecular-level initiating event with an adverse outcome at the cellular level for human health endpoints, or at the...
6.
Muller E, Lika K, Nisbet R, Schultz I, Casas J, Gergs A, et al.
Funct Ecol . 2020 Feb; 33(5):819-832. PMID: 32038063
1. The simple bioenergetic models in the family of Dynamic Energy Budget (DEB) consist of a small number of state equations quantifying universal processes, such as feeding, maintenance, development, reproduction...
7.
Rowland M, Wear H, Watanabe K, Gust K, Mayo M
BMC Syst Biol . 2018 Aug; 12(1):81. PMID: 30086736
Background: A challenge of in vitro to in vivo extrapolation (IVIVE) is to predict the physical state of organisms exposed to chemicals in the environment from in vitro exposure assay...
8.
Murphy C, Nisbet R, Antczak P, Garcia-Reyero N, Gergs A, Lika K, et al.
Integr Environ Assess Manag . 2018 Jun; 14(5):615-624. PMID: 29870141
A working group at the National Institute for Mathematical and Biological Synthesis (NIMBioS) explored the feasibility of integrating 2 complementary approaches relevant to ecological risk assessment. Adverse outcome pathway (AOP)...
9.
Wear H, Eriksson A, Hung-Chang Yao H, Watanabe K
Biol Reprod . 2017 Nov; 97(3):365-377. PMID: 29088396
Despite its importance to reproduction, certain mechanisms of early ovarian development remain a mystery. To improve our understanding, we constructed the first cell-based computational model of ovarian development in mice...
10.
Conolly R, Ankley G, Cheng W, Mayo M, Miller D, Perkins E, et al.
Environ Sci Technol . 2017 Mar; 51(8):4661-4672. PMID: 28355063
A quantitative adverse outcome pathway (qAOP) consists of one or more biologically based, computational models describing key event relationships linking a molecular initiating event (MIE) to an adverse outcome. A...