Kathleen M Jensen
Overview
Explore the profile of Kathleen M Jensen including associated specialties, affiliations and a list of published articles.
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78
Citations
884
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Recent Articles
1.
Ankley G, Jensen K, Cavallin J, Baettig C, Balgooyen S, Blackwell B, et al.
Environ Toxicol Chem
. 2025 Feb;
44(3):786-801.
PMID: 39918401
Effects data are lacking for the majority of poly- and perfluoroalkyl substances (PFAS). Recent in vitro work with around 140 data-poor PFAS showed that several could affect signaling pathways associated...
2.
Santana Rodriguez K, Villeneuve D, Cavallin J, Blackwell B, Hoang J, Hofer R, et al.
Environ Toxicol Chem
. 2024 Jul;
PMID: 38961679
In a previous in vivo study, adult male fathead minnows (Pimephales promelas) were exposed via water for 4 days to 1H,1H,8H,8H-perfluorooctane-1,8-diol (FC8-diol). The present study expands on the evaluation of...
3.
Gust K, Mylroie J, Kimble A, Wilbanks M, Steward C, Chapman K, et al.
Environ Toxicol Chem
. 2023 Nov;
43(1):115-131.
PMID: 38018867
A prior multigenerational perfluorooctane sulfonic acid (PFOS) exposure investigation in zebrafish reported adverse effects at 0.734 µg/L, among the lowest aquatic effect levels for PFOS reported to date. The present...
4.
Morshead M, Jensen K, Ankley G, Vliet S, LaLone C, Aller A, et al.
Aquat Toxicol
. 2023 Jun;
261:106607.
PMID: 37354817
Several adverse outcome pathways (AOPs) have linked molecular initiating events like aromatase inhibition, androgen receptor (AR) agonism, and estrogen receptor (ER) antagonism to reproductive impairment in adult fish. Estrogen receptor...
5.
Ankley G, Santana-Rodriguez K, Jensen K, Miller D, Villeneuve D
Environ Toxicol Chem
. 2023 Feb;
42(4):747-756.
PMID: 36848318
Screening and testing of potential endocrine-disrupting chemicals for ecological effects are examples of risk assessment/regulatory activities that can employ adverse outcome pathways (AOPs) to establish linkages between readily measured alterations...
6.
Villeneuve D, Blackwell B, Cavallin J, Collins J, Hoang J, Hofer R, et al.
Environ Sci Technol
. 2023 Feb;
57(9):3794-3803.
PMID: 36800546
Given concerns about potential toxicological hazards of the thousands of data-poor per- and polyfluorinated alkyl substances (PFAS) currently in commerce and detected in the environment, tiered testing strategies that employ...
7.
Maloney E, Villeneuve D, Jensen K, Blackwell B, Kahl M, Poole S, et al.
Environ Toxicol Chem
. 2023 Jan;
42(6):1229-1256.
PMID: 36715369
Anthropogenic activities introduce complex mixtures into aquatic environments, necessitating mixture toxicity evaluation during risk assessment. There are many alternative approaches that can be used to complement traditional techniques for mixture...
8.
Maloney E, Villeneuve D, Blackwell B, Vitense K, Corsi S, Pronschinske M, et al.
Integr Environ Assess Manag
. 2022 Dec;
19(5):1276-1296.
PMID: 36524447
Watersheds are subjected to diverse anthropogenic inputs, exposing aquatic biota to a wide range of chemicals. Detection of multiple, different chemicals can challenge natural resource managers who often have to...
9.
Villeneuve D, Blackwell B, Blanksma C, Cavallin J, Cheng W, Conolly R, et al.
Environ Toxicol Chem
. 2022 Oct;
42(1):100-116.
PMID: 36282016
To reduce the use of intact animals for chemical safety testing, while ensuring protection of ecosystems and human health, there is a demand for new approach methodologies (NAMs) that provide...
10.
Blackwell B, Ankley G, Biales A, Cavallin J, Cole A, Collette T, et al.
Environ Toxicol Chem
. 2022 Aug;
41(11):2708-2720.
PMID: 35920346
Metformin, along with its biotransformation product guanylurea, is commonly observed in municipal wastewaters and subsequent surface waters. Previous studies in fish have identified metformin as a potential endocrine-active compound, but...