Karam Mounzer
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Explore the profile of Karam Mounzer including associated specialties, affiliations and a list of published articles.
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95
Citations
1722
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Recent Articles
1.
Moskovljevic M, Dragoni F, Board N, Wu F, Lai J, Zhang H, et al.
Immunity
. 2024 Nov;
57(12):2928-2944.e6.
PMID: 39612916
Despite antiretroviral therapy (ART), HIV-1 persists in latently infected CD4 T cells, preventing a cure. Antigens drive the proliferation of infected cells, precluding latent reservoir decay. However, the relationship between...
2.
Maguire C, Rueve K, Farmer E, Huesgen E, Karaj A, Binkley A, et al.
Clin Infect Dis
. 2024 Nov;
PMID: 39602809
Background: The first long-acting injectable antiretroviral, cabotegravir/rilpivirine (LA-CAB/RPV), was FDA approved in January 2021 for persons with HIV suppressed on their current regimen. Body mass index (BMI) ≥30 kg/m2 has...
3.
Kelley C, Acevedo-Quinones M, Agwu A, Avihingsanon A, Benson P, Blumenthal J, et al.
N Engl J Med
. 2024 Nov;
PMID: 39602624
Background: Twice-yearly subcutaneous lenacapavir has been shown to be efficacious for prevention of HIV infection in cisgender women. The efficacy of lenacapavir for preexposure prophylaxis (PrEP) in cisgender men, transgender...
4.
Mounzer K, Slim J, Ramgopal M, Hedgcock M, Bloch M, Santana J, et al.
Clin Infect Dis
. 2024 Nov;
PMID: 39589133
Background: Complex antiretroviral therapy (ART) regimens, such as those requiring multiple tablets, several doses per day, or both, can negatively affect quality of life and treatment adherence among people with...
5.
Papasavvas E, Lu L, Fair M, Oliva I, Cassel J, Majumdar S, et al.
J Immunol
. 2024 Aug;
213(6):808-822.
PMID: 39109927
Type I IFNs play a pivotal role in immune response modulation, yet dysregulation is implicated in various disorders. Therefore, it is crucial to develop tools that facilitate the understanding of...
6.
Wohl D, Spinner C, Flamm J, Hare C, Doblecki-Lewis S, Ruane P, et al.
Lancet HIV
. 2024 Jul;
11(8):e508-e521.
PMID: 39008999
Background: Data characterising the long-term use and safety of emtricitabine plus tenofovir disoproxil fumarate as daily oral pre-exposure prophylaxis (PrEP) are scarce and there are uncertainties regarding the value of...
7.
Papasavvas E, Lu L, Fair M, Oliva I, Cassel J, Majumdar S, et al.
bioRxiv
. 2024 May;
PMID: 38746170
Type I interferons (IFNs) play a pivotal role in immune response modulation, yet dysregulation is implicated in various disorders. Therefore, it is crucial to develop tools that facilitate the understanding...
8.
Bilger A, Plenn E, Barg F, Rendle K, Carter W, Lamour-Harrington A, et al.
HIV Res Clin Pract
. 2023 Oct;
24(1):2267825.
PMID: 37837376
Background: A feature of HIV cure trials is the need to interrupt treatment to test the efficacy of experimental interventions-a process known as analytical treatment interruptions (ATIs). Objectives: We report...
9.
McMyn N, Varriale J, Fray E, Zitzmann C, MacLeod H, Lai J, et al.
J Clin Invest
. 2023 Jul;
133(17).
PMID: 37463049
HIV-1 persists in a latent reservoir in resting CD4+ T cells despite antiretroviral therapy (ART). The reservoir decays slowly over the first 7 years of ART (t1/2 = 44 months)....
10.
Tebas P, Lynn K, Azzoni L, Cocchella G, Papasavvas E, Fair M, et al.
AIDS
. 2023 Apr;
37(8):1203-1207.
PMID: 37070542
Objective: The aim of this study was to assess the susceptibility of HIV to two HIV monoclonal antibodies (bnAbs), 3BNC117 and 10-1074, in individuals with chronically antiretroviral therapy (ART) suppressed...