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Kara Dolinski

Explore the profile of Kara Dolinski including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 6022
Followers 0
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Recent Articles
1.
Sokolova K, Theesfeld C, Wong A, Zhang Z, Dolinski K, Troyanskaya O
Cell Rep Methods . 2023 Sep; 3(9):100580. PMID: 37703883
Human biology is rooted in highly specialized cell types programmed by a common genome, 98% of which is outside of genes. Genetic variation in the enormous noncoding space is linked...
2.
Chatr-Aryamontri A, Hirschman L, Ross K, Oughtred R, Krallinger M, Dolinski K, et al.
Database (Oxford) . 2022 Oct; 2022. PMID: 36197453
The coronavirus disease 2019 (COVID-19) pandemic has compelled biomedical researchers to communicate data in real time to establish more effective medical treatments and public health policies. Nontraditional sources such as...
3.
Oughtred R, Rust J, Chang C, Breitkreutz B, Stark C, Willems A, et al.
Protein Sci . 2020 Oct; 30(1):187-200. PMID: 33070389
The BioGRID (Biological General Repository for Interaction Datasets, thebiogrid.org) is an open-access database resource that houses manually curated protein and genetic interactions from multiple species including yeast, worm, fly, mouse,...
4.
Roussarie J, Yao V, Rodriguez-Rodriguez P, Oughtred R, Rust J, Plautz Z, et al.
Neuron . 2020 Jul; 107(5):821-835.e12. PMID: 32603655
A major obstacle to treating Alzheimer's disease (AD) is our lack of understanding of the molecular mechanisms underlying selective neuronal vulnerability, a key characteristic of the disease. Here, we present...
5.
Lee Y, Krishnan A, Oughtred R, Rust J, Chang C, Ryu J, et al.
Cell Syst . 2019 Jan; 8(2):152-162.e6. PMID: 30685436
A key challenge for the diagnosis and treatment of complex human diseases is identifying their molecular basis. Here, we developed a unified computational framework, URSA (Unveiling RNA Sample Annotation for...
6.
Dong S, Lau V, Song R, Ierullo M, Esteban E, Wu Y, et al.
Plant Physiol . 2019 Jan; 179(4):1893-1907. PMID: 30679268
Determining the complete Arabidopsis () protein-protein interaction network is essential for understanding the functional organization of the proteome. Numerous small-scale studies and a couple of large-scale ones have elucidated a...
7.
Oughtred R, Stark C, Breitkreutz B, Rust J, Boucher L, Chang C, et al.
Nucleic Acids Res . 2018 Nov; 47(D1):D529-D541. PMID: 30476227
The Biological General Repository for Interaction Datasets (BioGRID: https://thebiogrid.org) is an open access database dedicated to the curation and archival storage of protein, genetic and chemical interactions for all major...
8.
Islamaj Dogan R, Kim S, Chatr-Aryamontri A, Chang C, Oughtred R, Rust J, et al.
Database (Oxford) . 2017 Jan; 2017. PMID: 28077563
A great deal of information on the molecular genetics and biochemistry of model organisms has been reported in the scientific literature. However, this data is typically described in free text...
9.
Chatr-Aryamontri A, Oughtred R, Boucher L, Rust J, Chang C, Kolas N, et al.
Nucleic Acids Res . 2016 Dec; 45(D1):D369-D379. PMID: 27980099
The Biological General Repository for Interaction Datasets (BioGRID: https://thebiogrid.org) is an open access database dedicated to the annotation and archival of protein, genetic and chemical interactions for all major model...
10.
Kim S, Islamaj Dogan R, Chatr-Aryamontri A, Chang C, Oughtred R, Rust J, et al.
Database (Oxford) . 2016 Sep; 2016. PMID: 27589962
BioC is a simple XML format for text, annotations and relations, and was developed to achieve interoperability for biomedical text processing. Following the success of BioC in BioCreative IV, the...