Kanta Chandwe
Overview
Explore the profile of Kanta Chandwe including associated specialties, affiliations and a list of published articles.
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30
Citations
250
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Recent Articles
1.
Sturgeon J, Mutasa K, Bwakura-Dangarembizi M, Amadi B, Ngosa D, Dzikiti A, et al.
EBioMedicine
. 2024 Dec;
111():105478.
PMID: 39662176
Background: Severe acute malnutrition (SAM) is the most life-threatening form of undernutrition, and children hospitalised with complications have unacceptably high mortality. Complicated SAM is a multisystem disease characterised pathophysiologically by...
2.
Iqbal N, Lawrence S, Ahmed T, Chandwe K, Fahim S, Houpt E, et al.
Am J Clin Nutr
. 2024 Sep;
120 Suppl 1:S84-S93.
PMID: 39300666
Background: Environmental Enteric Dysfunction (EED) is an acquired disorder of asymptomatic altered gut function, the etiology of which is unknown. EED is postulated to be a major contributor to growth...
3.
Mahfuz M, Coomes D, Abdalla M, Mweetwa M, VanBuskirk K, Iqbal N, et al.
Am J Clin Nutr
. 2024 Sep;
120 Suppl 1:S73-S83.
PMID: 39300665
Background: Validated biomarkers could catalyze environmental enteric dysfunction (EED) research. Objectives: Leveraging an EED histology scoring system, this multicountry analysis examined biomarker associations with duodenal histology features among children with...
4.
Jamil Z, VanBuskirk K, Mweetwa M, Mouksassi S, Smith G, Ahmed T, et al.
Am J Clin Nutr
. 2024 Sep;
120 Suppl 1:S65-S72.
PMID: 39300664
Background: Environmental enteric dysfunction (EED) is a precursor of growth faltering in children living in impoverished conditions who are frequently exposed to environmental toxins and enteropathogens, leading to small bowel...
5.
Chandwe K, Bwakura-Dangarembizi M, Amadi B, Tawodzera G, Ngosa D, Dzikiti A, et al.
Nat Commun
. 2024 Apr;
15(1):2910.
PMID: 38632262
Malnutrition underlies almost half of all child deaths globally. Severe Acute Malnutrition (SAM) carries unacceptable mortality, particularly if accompanied by infection or medical complications, including enteropathy. We evaluated four interventions...
6.
Sturgeon J, Tome J, Dumbura C, Majo F, Ngosa D, Mutasa K, et al.
Sci Transl Med
. 2024 Feb;
16(736):eadh0673.
PMID: 38416844
Severe acute malnutrition (SAM) is the most high-risk form of undernutrition, particularly when children require hospitalization for complications. Complicated SAM is a multisystem disease with high inpatient and postdischarge mortality,...
7.
Malique A, Sun S, Chandwe K, Amadi B, Haritunians T, Jain U, et al.
Sci Transl Med
. 2024 Jan;
16(728):eabq4145.
PMID: 38170788
Environmental enteric dysfunction (EED) is a diffuse small bowel disorder associated with poor growth, inadequate responses to oral vaccines, and nutrient malabsorption in millions of children worldwide. We identify loss...
8.
Phiri T, Mutasa K, Rukobo S, Govha M, Mushayanembwa P, Mwakamui S, et al.
Sci Adv
. 2023 Nov;
9(44):eadh2284.
PMID: 37910623
Children with severe acute malnutrition (SAM) have high infectious mortality and morbidity, implicating defects in their immune defenses. We hypothesized that circulating innate immune cells from children (0 to 59...
9.
Mweetwa M, Haritunians T, Dube S, Chandwe K, Amadi B, Zyambo K, et al.
PLoS One
. 2023 Sep;
18(9):e0291311.
PMID: 37756315
Purpose: Stunting is known to be heavily influenced by environmental factors, so the genetic contribution has received little attention. Here we report an exploration of genetic influences in stunted Zambian...
10.
Sturgeon J, Mufukari W, Tome J, Dumbura C, Majo F, Ngosa D, et al.
Eur J Clin Nutr
. 2023 Aug;
77(9):895-904.
PMID: 37553508
Background/objectives: Malnutrition underlies 45% of deaths in children under-5 years annually. Children hospitalised with complicated severe acute malnutrition (SAM) have unacceptably high mortality. We aimed to identify variables from early...