Kam C Yeung
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Explore the profile of Kam C Yeung including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
733
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Recent Articles
1.
Kalpana G, Figy C, Feng J, Tipton C, De Castro J, Bach V, et al.
Sci Rep
. 2023 Jul;
13(1):11293.
PMID: 37438425
No abstract available.
2.
Argueta C, Figy C, Bouali S, Guo A, Yeung K, Fenteany G
J Biol Chem
. 2023 Feb;
299(4):103023.
PMID: 36805338
Raf kinase inhibitor protein (RKIP) is a multifunctional modulator of intracellular signal transduction. Although most of its functions have been considered cytosolic, we show here that the localization of RKIP...
3.
Figy C, Guo A, Fernando V, Furuta S, Al-Mulla F, Yeung K
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765912
Tumor microenvironment (TME) is the immediate environment where cancer cells reside in a tumor. It is composed of multiple cell types and extracellular matrix. Microenvironments can be restrictive or conducive...
4.
Bach V, Ding J, Yeung M, Conrad T, Odeh H, Cubberly P, et al.
Cancers (Basel)
. 2022 Jul;
14(15).
PMID: 35892864
Raf-1 kinase inhibitor protein was first identified as a negative regulator of the Raf signaling pathway. Subsequently, it was shown to have a causal role in containing cancer progression and...
5.
Kalpana G, Figy C, Feng J, Tipton C, De Castro J, Bach V, et al.
Sci Rep
. 2021 Sep;
11(1):17455.
PMID: 34465801
Raf-1 kinase inhibitor protein was initially discovered as a physiological kinase inhibitor of the MAPK signaling pathway and was later shown to suppress cancer cell invasion and metastasis. Yet, the...
6.
Kalpana G, Figy C, Yeung M, Yeung K
Sci Rep
. 2019 Nov;
9(1):16351.
PMID: 31705019
The role of RhoA GTPases in breast cancer tumorigenesis and metastasis is unclear. Early studies within which mutations in RhoA were designed based on cancer-associated mutations in Ras supported an...
7.
Datar I, Kalpana G, Choi J, Basuroy T, Trumbly R, Arudra S, et al.
PLoS One
. 2019 Apr;
14(4):e0204387.
PMID: 30995246
Recent high-throughput-sequencing of cancer genomes has identified oncogenic mutations in the B-Raf genetic locus as one of the critical events in melanomagenesis. B-Raf encodes a serine/threonine kinase that regulates the...
8.
Datar I, Qiu X, Zhi Ma H, Yeung M, Aras S, de la Serna I, et al.
Oncotarget
. 2016 Aug;
7(18):26925.
PMID: 27532884
Present: Due to an error made by the authors while submitting a revision, Dr. Tuan Zea Tan was omitted from the list of authors.Corrected: Correct author list can be found...
9.
Datar I, Qiu X, Zhi Ma H, Yeung M, Aras S, de la Serna I, et al.
Oncotarget
. 2015 Sep;
6(36):39050-61.
PMID: 26375811
Accumulating evidence suggests that presence of macrophages in the tumor microenvironment add to the invasive and tumor-promoting hallmarks of cancer cells by secreting angiogenic and growth factors. RKIP is a...
10.
Datar I, Feng J, Qiu X, Lewandowski J, Yeung M, Ren G, et al.
PLoS One
. 2015 Aug;
10(8):e0134494.
PMID: 26308852
Raf Kinase Inhibitory Protein or RKIP was initially identified as a Raf-1 binding protein using the yeast 2-hybrid screen. RKIP inhibits the activation phosphorylation of MEK by Raf-1 by competitively...