Kaja Nordengen
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Explore the profile of Kaja Nordengen including associated specialties, affiliations and a list of published articles.
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20
Citations
264
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Recent Articles
1.
Vold V, Tingvoll S, Beyer M, Nordengen K
Front Neuroimaging
. 2025 Mar;
4:1436931.
PMID: 40034189
Cytotoxic lesions of the corpus callosum (CLOCC) are a clinicoradiological diagnosis, characterized by transient neurological symptoms and magnetic resonance imaging (MRI) changes in the splenium of the corpus callosum (SCC),...
2.
Jaholkowski P, Bahrami S, Fominykh V, Hindley G, Tesfaye M, Parekh P, et al.
Neurobiol Dis
. 2024 Nov;
203:106750.
PMID: 39608471
The observation that the risk of developing Alzheimer's disease is reduced in individuals with high premorbid cognitive functioning, higher educational attainment, and occupational status has led to the 'cognitive reserve'...
3.
Bahrami S, Nordengen K, Rokicki J, Shadrin A, Rahman Z, Smeland O, et al.
Nat Commun
. 2024 Oct;
15(1):8476.
PMID: 39353893
The basal ganglia are subcortical brain structures involved in motor control, cognition, and emotion regulation. We conducted univariate and multivariate genome-wide association analyses (GWAS) to explore the genetic architecture of...
4.
Distribution of lipid droplets in hippocampal neurons and microglia: impact of diabetes and exercise
Seferi G, Mjones H, Havik M, Reiersen H, Dalen K, Nordengen K, et al.
Life Sci Alliance
. 2024 Aug;
7(10).
PMID: 39117458
Neuroinflammation, aging, and neurodegenerative disorders are associated with excessive accumulation of neutral lipids in lipid droplets (LDs) in microglia. Type 2 diabetes mellitus (T2DM) may cause neuroinflammation and is a...
5.
Knudtzon S, Nordengen K, Grontvedt G, Jarholm J, Eliassen I, Selnes P, et al.
Neurobiol Aging
. 2024 Jun;
141:74-84.
PMID: 38838442
Cerebrospinal fluid total-tau (t-tau) and neurofilament light chain (NfL) are biomarkers of neurodegeneration and are increased in Alzheimer's disease (AD). In order to adjust for age-related increases in t-tau and...
6.
Nordengen K, Morland C
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38256059
Alpha-synuclein (α-syn) has gained significant attention due to its involvement in neurodegenerative diseases, particularly Parkinson's disease. However, its normal function in the human brain is equally fascinating. The α-syn protein...
7.
Nordengen K, Kirsebom B, Richter G, Palhaugen L, Gisladottir B, Siafarikas N, et al.
J Neuroinflammation
. 2023 Dec;
20(1):298.
PMID: 38093257
Background: Brain innate immune activation is associated with Alzheimer's disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal...
8.
Nordengen K, Cappelletti C, Bahrami S, Frei O, Pihlstrom L, Henriksen S, et al.
Brain
. 2023 Sep;
147(3):858-870.
PMID: 37671566
Parkinson's disease is an age-related neurodegenerative disorder with a higher incidence in males than females. The causes for this sex difference are unknown. Genome-wide association studies (GWAS) have identified 90...
9.
Jarholm J, Bjornerud A, Dalaker T, Akhavi M, Kirsebom B, Palhaugen L, et al.
J Alzheimers Dis
. 2023 May;
94(1):259-279.
PMID: 37248900
Background: Atrophy of the medial temporal lobe (MTL) is a biological characteristic of Alzheimer's disease (AD) and can be measured by segmentation of magnetic resonance images (MRI). Objective: To assess...
10.
Kirsebom B, Richter G, Nordengen K, Aarsland D, Brathen G, Tijms B, et al.
Brain Commun
. 2022 Oct;
4(5):fcac244.
PMID: 36262371
Cerebrospinal fluid (CSF) β-site amyloid precursor protein cleaving enzyme 1 (BACE1), neurogranin and the neurogranin/BACE1 ratio are proposed markers for Alzheimer's disease. BACE1 is also a drug target. However, CSF...