Kailing Tu
Overview
Explore the profile of Kailing Tu including associated specialties, affiliations and a list of published articles.
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10
Citations
143
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Recent Articles
1.
Tu K, Li X, Zhang Q, Huang W, Xie D
Bioinformatics
. 2024 Apr;
40(5).
PMID: 38613848
Motivation: Identifying chromatin accessibility is one of the key steps in studying the regulation of eukaryotic genomes. The combination of exogenous methyltransferase and nanopore sequencing provides an strategy to identify...
2.
Li X, Lu K, Chen X, Tu K, Xie D
Commun Biol
. 2023 Sep;
6(1):974.
PMID: 37741908
Transposable elements (TEs) serve as both insertional mutagens and regulatory elements in cells, and their aberrant activity is increasingly being revealed to contribute to diseases and cancers. However, measuring the...
3.
Tang J, Tu K, Lu K, Zhang J, Luo K, Jin H, et al.
Genome Med
. 2021 Sep;
13(1):148.
PMID: 34507604
Background: Colorectal cancer (CRC) is a major cancer type whose mechanism of metastasis remains elusive. Methods: In this study, we characterised the evolutionary pattern of metastatic CRC (mCRC) by analysing...
4.
Tu K, Lu K, Zhang Q, Huang W, Xie D
Nucleic Acids Res
. 2021 Feb;
49(10):e57.
PMID: 33619552
Single-nucleotide variant (SNV) detection in the genome of single cells is affected by DNA amplification artefacts, including imbalanced alleles and early PCR errors. Existing single-cell genotyper accuracy often depends on...
5.
Cao F, Wei A, Hu X, He Y, Zhang J, Xia L, et al.
Clin Epigenetics
. 2020 Jul;
12(1):112.
PMID: 32703318
Background: The high lethal rate of pancreatic cancer is partly due to a lack of efficient biomarkers for screening and early diagnosis. We attempted to develop effective and noninvasive methods...
6.
Wang Z, Tu K, Xia L, Luo K, Luo W, Tang J, et al.
Cancer Res
. 2019 Jun;
79(19):4840-4854.
PMID: 31209061
Non-small cell lung carcinoma (NSCLC) is a major cancer type whose epigenetic alteration remains unclear. We analyzed open chromatin data with matched whole-genome sequencing and RNA-seq data of 50 primary...
7.
Chen R, Xia L, Tu K, Duan M, Kukurba K, Li-Pook-Than J, et al.
Nat Med
. 2018 Nov;
24(12):1930-1939.
PMID: 30397358
Epigenomics regulates gene expression and is as important as genomics in precision personal health, as it is heavily influenced by environment and lifestyle. We profiled whole-genome DNA methylation and the...
8.
Tan T, Xia L, Tu K, Tang J, Yin S, Dai L, et al.
BMC Genomics
. 2018 Nov;
19(1):787.
PMID: 30382841
Backgrounds: Macaca fascicularis (M. fascicularis) is a primate model organism that played important role in studying human health. It is vital to better understand the similarity and differences of gene...
9.
Zhou L, Jiang S, Fu Q, Smith K, Tu K, Li H, et al.
Oncol Rep
. 2016 Mar;
35(5):2715-22.
PMID: 26936618
Both fatty acid synthase (FASN) and ErbB2 have been shown to promote breast cancer cell migration. However, the underlying molecular mechanism remains poorly understood and there is no reported evidence...
10.
Jiang S, Tu K, Fu Q, Schmitt D, Zhou L, Lu N, et al.
Tumour Biol
. 2015 Jun;
36(7):4923-31.
PMID: 26108999
Heat shock transcription factor 1 (HSF1) is the master regulator of the heat shock response. Accumulating evidence shows that HSF1 is overexpressed in a variety of human cancers, is associated...