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Kai-Thomas Schneider

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Articles 8
Citations 176
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Recent Articles
1.
Ballmann R, Schneider K, Roth K, Dubel S
Methods Mol Biol . 2023 Sep; 2702:411-417. PMID: 37679632
The antigen-binding ability of each antibody clone selected by phage display is usually initially ranked by a screening ELISA using monovalent scFv antibody fragments. Further characterization often requires bivalent antibody...
2.
Steinke S, Roth K, Ruschig M, Langreder N, Polten S, Schneider K, et al.
Methods Mol Biol . 2023 Sep; 2702:247-260. PMID: 37679623
The most common and robust in vitro technology to generate monoclonal human antibodies is phage display. This technology is a widely used and powerful key technology for recombinant antibody selection....
3.
Jaron M, Lehky M, Zara M, Zaydowicz C, Lak A, Ballmann R, et al.
Viruses . 2022 Oct; 14(10). PMID: 36298643
Virus-like particles (VLPs) resemble authentic virus while not containing any genomic information. Here, we present a fast and powerful method for the production of SARS-CoV-2 VLP in insect cells and...
4.
Russo G, Unkauf T, Meier D, Wenzel E, Langreder N, Schneider K, et al.
Biol Chem . 2022 Mar; 403(5-6):479-494. PMID: 35312243
One of the most widely used epitope tags is the myc-tag, recognized by the anti-c-Myc hybridoma antibody Myc1-9E10. Combining error-prone PCR, DNA shuffling and phage display, we generated an anti-c-Myc...
5.
Schneider K, Kirmann T, Wenzel E, Grosch J, Polten S, Meier D, et al.
Front Cell Infect Microbiol . 2021 Dec; 11:717689. PMID: 34869052
Generation of sequence defined antibodies from universal libraries by phage display has been established over the past three decades as a robust method to cope with the increasing market demand...
6.
Roth K, Wenzel E, Ruschig M, Steinke S, Langreder N, Heine P, et al.
Front Cell Infect Microbiol . 2021 Jul; 11:697876. PMID: 34307196
Antibodies are essential molecules for diagnosis and treatment of diseases caused by pathogens and their toxins. Antibodies were integrated in our medical repertoire against infectious diseases more than hundred years...
7.
Bertoglio F, Fuhner V, Ruschig M, Heine P, Abassi L, Klunemann T, et al.
Cell Rep . 2021 Jul; 36(4):109433. PMID: 34273271
The novel betacoronavirus severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) causes a form of severe pneumonia disease called coronavirus disease 2019 (COVID-19). To develop human neutralizing anti-SARS-CoV-2 antibodies, antibody gene libraries from...
8.
Bertoglio F, Meier D, Langreder N, Steinke S, Rand U, Simonelli L, et al.
Nat Commun . 2021 Mar; 12(1):1577. PMID: 33707427
COVID-19 is a severe acute respiratory disease caused by SARS-CoV-2, a new recently emerged sarbecovirus. This virus uses the human ACE2 enzyme as receptor for cell entry, recognizing it with...