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Kai-Shun Chen

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Articles 10
Citations 260
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Recent Articles
1.
Deng K, Wang S, Kiener S, Smith E, Chen K, Pamboukian R, et al.
Food Microbiol . 2023 Jun; 114:104299. PMID: 37290875
The FDA Bacteriological Analytical Manual (BAM) Salmonella culture method takes at least 3 days for a presumptive positive result. The FDA developed a quantitative PCR (qPCR) method to detect Salmonella...
2.
Cheng C, Doran T, Lin W, Chen K, Williams-Hill D, Pamboukian R
J Food Prot . 2015 Jun; 78(6):1119-24. PMID: 26038901
Sixteen FERN (Food Emergency Response Network) member laboratories collaborated in this study to verify extension of the real-time PCR Salmonella detection method originally designed for the single-tube Cepheid SmartCycler II...
3.
Pierce S, Bell R, Hellberg R, Cheng C, Chen K, Williams-Hill D, et al.
Appl Environ Microbiol . 2012 Sep; 78(23):8403-11. PMID: 23001674
An assay to identify the common food-borne pathogens Salmonella, Escherichia coli, Shigella, and Listeria monocytogenes was developed in collaboration with Ibis Biosciences (a division of Abbott Molecular) for the Plex-ID...
4.
Beaubrun J, Cheng C, Chen K, Ewing L, Wang H, Agpaoa M, et al.
Food Microbiol . 2012 May; 31(2):199-209. PMID: 22608224
The most commonly used method for serotyping Salmonella spp. is based on the Kaufmann-White scheme, and is composed of serological reactions using antibodies to LPS agglutinins. The multiplex PCR used...
5.
Samuelson D, Hesselson S, Aperavich B, Zan Y, Haag J, Trentham-Dietz A, et al.
Proc Natl Acad Sci U S A . 2007 Apr; 104(15):6299-304. PMID: 17404222
Breast cancer risk is a polygenic trait. To identify breast cancer modifier alleles that have a high population frequency and low penetrance we used a comparative genomics approach. Quantitative trait...
6.
Amos-Landgraf J, Kwong L, Kendziorski C, Reichelderfer M, Torrealba J, Weichert J, et al.
Proc Natl Acad Sci U S A . 2007 Mar; 104(10):4036-41. PMID: 17360473
Progress toward the understanding and management of human colon cancer can be significantly advanced if appropriate experimental platforms become available. We have investigated whether a rat model carrying a knockout...
7.
Berchtold C, Chen K, Miyamoto S, Gould M
Cancer Res . 2005 Sep; 65(18):8558-66. PMID: 16166337
The cell death induced by the monoterpene anticancer agent perillyl alcohol correlates to the increased expression of certain proapoptotic genes known to influence cell survival. Whereas sequence-specific DNA-binding factors dictate...
8.
Chen K, Gould M
Biotechniques . 2004 Oct; 37(3):383-8. PMID: 15470892
Recently, we reported the production of the first knockout rats by combining N-ethyl-N-nitrosourea (ENU)-induced mutagenesis with a yeast-based truncation screening method. To make this new knockout technology more applicable for...
9.
Zan Y, Haag J, Chen K, Shepel L, Wigington D, Wang Y, et al.
Nat Biotechnol . 2003 May; 21(6):645-51. PMID: 12754522
The rat is a widely used model in biomedical research and is often the preferred rodent model in many areas of physiological and pathobiological research. Although many genetic tools are...
10.
Watson P, Kim K, Chen K, Gould M
Cancer Cell . 2002 Aug; 2(1):67-79. PMID: 12150826
Transgenic rats were created with overexpression of the Neu proto-oncogene in the mammary gland of both sexes, yet only males developed mammary cancer in an androgen-dependent fashion. Transgenic females only...