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Kaare M Gautvik

Explore the profile of Kaare M Gautvik including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 1513
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Recent Articles
1.
Reppe S, Reseland J, Prijatelj V, Prediger M, Nogueira L, Utheim T, et al.
Int J Mol Sci . 2024 Dec; 25(23). PMID: 39684435
This study explores how select microRNAs (miRNAs) influence bone structure in humans and in transgenic mice. In trabecular bone biopsies from 84 postmenopausal women (healthy, osteopenic, and osteoporotic), we demonstrate...
2.
Reppe S, Gundersen S, Sandve G, Wang Y, Andreassen O, Medina-Gomez C, et al.
Int J Mol Sci . 2024 May; 25(10). PMID: 38791593
Epidemiological evidence suggests existing comorbidity between postmenopausal osteoporosis (OP) and cardiovascular disease (CVD), but identification of possible shared genes is lacking. The skeletal global transcriptomes were analyzed in trans-iliac bone...
3.
Medina-Gomez C, Mullin B, Chesi A, Prijatelj V, Kemp J, Shochat-Carvalho C, et al.
Commun Biol . 2023 Jul; 6(1):691. PMID: 37402774
Skull bone mineral density (SK-BMD) provides a suitable trait for the discovery of key genes in bone biology, particularly to intramembranous ossification, not captured at other skeletal sites. We perform...
4.
Zheng J, Wheeler E, Pietzner M, Andlauer T, Yau M, Hartley A, et al.
Arthritis Rheumatol . 2023 Apr; 75(10):1781-1792. PMID: 37096546
Objective: In this study, we aimed to establish the causal effects of lowering sclerostin, target of the antiosteoporosis drug romosozumab, on atherosclerosis and its risk factors. Methods: A genome-wide association...
5.
Brodholt E, Gautvik K, Gunther C, Sjovold T, Holck P
PLoS One . 2022 Oct; 17(10):e0275448. PMID: 36260599
This study presents skeletal material from five medieval burial sites in Eastern Norway, confined to one royal burial church, one Dominican monastery, and three burial sites representing parish populations. We...
6.
Gautvik K, Olstad O, Raue U, Gautvik V, Kvernevik K, Utheim T, et al.
Eur Rev Aging Phys Act . 2022 Oct; 19(1):23. PMID: 36182918
Background: A striking effect of old age is the involuntary loss of muscle mass and strength leading to sarcopenia and reduced physiological functions. However, effects of heavy-load exercise in older...
7.
Gautvik K, Sachse D, Hinton A, Olstad O, Kiel D, Hsu Y, et al.
BMC Genom Data . 2022 Jul; 23(1):57. PMID: 35879676
Background: Physical molecular interactions are the basis of intracellular signalling and gene regulatory networks, and comprehensive, accessible databases are needed for their discovery. Highly correlated transcripts may reflect important functional...
8.
Datta H, Kringen M, Tuck S, Salpingidou G, Olstad O, Gautvik K, et al.
Int J Mol Sci . 2022 Mar; 23(6). PMID: 35328378
Mechanical loading exerts a profound influence on bone density and architecture, but the exact mechanism is unknown. Our study shows that expression of the neurological transcriptional factor zinc finger of...
9.
Maurizi A, Ponzetti M, Gautvik K, Reppe S, Teti A, Rucci N
Bone Rep . 2021 May; 14:101059. PMID: 34026950
Purpose: Lipocalin 2 (LCN2) is an adipokine involved in many physiological functions, including bone metabolism. We previously demonstrated its implication in mouse models of mechanical unloading-induced osteoporosis and in a...
10.
Gautvik K, Gunther C, Prijatelj V, Medina-Gomez C, Shevroja E, Rad L, et al.
J Bone Miner Res . 2020 Feb; 35(6):1065-1076. PMID: 32017184
We investigated mechanisms resulting in low bone mineral density (BMD) and susceptibility to fracture by comparing noncoding RNAs (ncRNAs) in biopsies of non-weight-bearing (NWB) iliac (n = 84) and weight...