Ka Yee C Lee
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Explore the profile of Ka Yee C Lee including associated specialties, affiliations and a list of published articles.
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76
Citations
1432
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Recent Articles
1.
Maltseva S, Kerr D, Turke M, Adams E, Lee K
Biophys J
. 2024 May;
123(12):1610-1619.
PMID: 38702883
Lipid-binding properties of α-synuclein play a central role in protein aggregation and progression of Parkinson's disease (PD). α-Synuclein, an intrinsically disordered protein, binds to lipid membranes through the formation of...
2.
Kerr D, Suwatthee T, Maltseva S, Lee K
Biophys J
. 2024 Mar;
123(7):885-900.
PMID: 38433448
The specific recognition of peripheral membrane-binding proteins for their target membranes is mediated by a complex constellation of various lipid contacts. Despite the inherent complexities of the heterogeneous protein-membrane interface,...
3.
Suwatthee T, Kerr D, Maltseva S, Dulberger C, Hwang L, Slaw B, et al.
Eur Phys J E Soft Matter
. 2023 Nov;
46(11):114.
PMID: 37999806
Membrane-binding proteins often associate with lipid membranes through a singular binding interface which is generally modeled as a two-state system: bound or unbound. However, even a single interface can engage...
4.
Chung P, Zhang Q, Hwang H, Leong A, Maj P, Szczygiel R, et al.
ACS Appl Bio Mater
. 2022 Jan;
2(4):1413-1419.
PMID: 35026915
While it is generally accepted that neuronal protein α-synuclein binds to highly curved and highly charged lipid membranes, its biological function beyond binding remains unknown despite its fundamental link to...
5.
Carotenuto A, Nguyen N, Cao K, Gaffney A, Waring A, Lee K, et al.
Curr Top Membr
. 2021 Oct;
87:1-45.
PMID: 34696882
Langmuir monolayers at gas/liquid interfaces provide a rich framework to investigate the interplay between multiscale geometry and mechanics. Monolayer collapse is investigated at a topological and geometric level by building...
6.
Kerr D, Gong Z, Suwatthee T, Luoma A, Roy S, Scarpaci R, et al.
Biophys J
. 2021 Sep;
120(21):4891-4902.
PMID: 34529946
Immune surveillance cells such as T cells and phagocytes utilize integral plasma membrane receptors to recognize surface signatures on triggered and activated cells such as those in apoptosis. One such...
7.
Wang J, Chen W, Nagao M, Shelat P, Hammer B, Tietjen G, et al.
Biomacromolecules
. 2019 Aug;
20(9):3385-3391.
PMID: 31424203
Some synthetic polymers can block cell death when applied following an injury that would otherwise kill the cell. This cellular rescue occurs through interactions of the polymers with cell membranes....
8.
Razavi S, Lin B, Lee K, Tu R, Kretzschmar I
Langmuir
. 2019 Jul;
35(48):15813-15824.
PMID: 31269790
Langmuir monolayers of silica/gold Janus particles with two different degrees of amphiphilicity have been examined to study the significance of particle surface amphiphilicity on the structure and mechanical properties of...
9.
Henderson J, Iyengar N, Lam K, Maldonado E, Suwatthee T, Roy I, et al.
Biochim Biophys Acta Biomembr
. 2019 May;
1861(10):182977.
PMID: 31077677
Antimicrobial peptides (AMPs) are a promising class of innate host defense molecules for next-generation antibiotics, as they uniquely target and permeabilize membranes of pathogens. This selectivity has been explained by...
10.
Chung P, Hwang H, Dasbiswas K, Leong A, Lee K
Langmuir
. 2018 Oct;
34(43):13000-13005.
PMID: 30303390
Spherical nanoparticle-supported lipid bilayers (SSLBs) combine precision nanoparticle engineering with biocompatible interfaces for various applications, ranging from drug delivery platforms to structural probes for membrane proteins. Although the bulk, spontaneous...