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K Tyc

Explore the profile of K Tyc including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 9
Citations 591
Followers 0
Related Specialties
Biochemistry
Molecular Biology
Cell Biology
Top 10 Co-Authors
J A Steitz
W Filipowicz
H J Gross
Y Kikuchi
S Kass
M Konarska
B Kastner
J P Bruzik
J Reichelt
H L Sanger
Published In
Nucleic Acids Res
EMBO J
Mol Cell Biol
Mol Biol Rep
J Biol Chem
Affiliations
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Recent Articles
1.
Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditions
Behrens S, Tyc K, Kastner B, Reichelt J, Luhrmann R
Mol Cell Biol . 1993 Jan; 13(1):307-19. PMID: 8380223
Small nuclear (sn) ribonucleoprotein (RNP) U2 functions in the splicing of mRNA by recognizing the branch site of the unspliced pre-mRNA. When HeLa nuclear splicing extracts are centrifuged on glycerol...
2.
A new interaction between the mouse 5' external transcribed spacer of pre-rRNA and U3 snRNA detected by psoralen crosslinking
Tyc K, Steitz J
Nucleic Acids Res . 1992 Oct; 20(20):5375-82. PMID: 1437554
The first cleavage in mammalian pre-rRNA processing occurs within the 5' external transcribed spacer (ETS). We have recently shown that the U3 snRNP is required for this cleavage reaction, binds...
3.
The U3 small nucleolar ribonucleoprotein functions in the first step of preribosomal RNA processing
Kass S, Tyc K, Steitz J
Cell . 1990 Mar; 60(6):897-908. PMID: 2156625
The first cleavage in mammalian pre-rRNA maturation occurs near the 5' end within the 5' external transcribed spacer. Using mouse cell extracts, we show that this processing is abolished by...
4.
Molecular analyses of the functions of SL and U3 snRNPs
Steitz J, Bruzik J, Tyc K, Kass S
Mol Biol Rep . 1990 Jan; 14(2-3):123. PMID: 1694557
No abstract available.
5.
U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus
Tyc K, Steitz J
EMBO J . 1989 Oct; 8(10):3113-9. PMID: 2531075
Using anti-(U3)RNP autoantibodies, we have isolated and characterized two additional small nucleolar RNAs from HeLa cells, which are less abundant than U3 RNA. Both RNAs possess a trimethylguanosine cap as...
6.
Purification and characterization of wheat germ 2',3'-cyclic nucleotide 3'-phosphodiesterase
Tyc K, Kellenberger C, Filipowicz W
J Biol Chem . 1987 Sep; 262(27):12994-3000. PMID: 3654600
The 2',3'-cyclic nucleotide 3'-phosphodiesterase which hydrolyzes nucleoside 2',3'-cyclic phosphates (N greater than p) to nucleoside 2'-phosphates has been purified 16,000-fold to near homogeneity from wheat germ. The purified enzyme is...
7.
Multiple ribosome binding to the 5'-terminal leader sequence of tobacco mosaic virus RNA. Assembly of an 80S ribosome X mRNA complex at the AUU codon
Tyc K, Konarska M, Gross H, Filipowicz W
Eur J Biochem . 1984 May; 140(3):503-11. PMID: 6723646
Tobacco mosaic virus (TMV) RNA with a long 5'-terminal leader sequence, as well as its isolated leader fragment (called omega), can form disome initiation complexes with wheat germ ribosomes. The...
8.
Ligation of endogenous tRNA 3' half molecules to their corresponding 5' halves via 2'-phosphomonoester,3',5'-phosphodiester bonds in extracts of Chlamydomonas
Tyc K, Kikuchi Y, Konarska M, Filipowicz W, Gross H
EMBO J . 1983 Jan; 2(4):605-10. PMID: 16453445
tRNA preparations from Chlamydomonas and wheat germ contain small amounts of tRNA 5' halves and corresponding 3' halves. Incubation of cell-free extracts from the two sources with [gamma-P]ATP yielded 5'-P-labeled...
9.
Circularization of linear viroid RNA via 2'-phosphomonoester, 3', 5'-phosphodiester bonds by a novel type of RNA ligase from wheat germ and Chlamydomonas
Kikuchi Y, Tyc K, Filipowicz W, Sanger H, Gross H
Nucleic Acids Res . 1982 Dec; 10(23):7521-9. PMID: 6760127
A novel type of RNA ligase activity in extracts of wheat germ or Chlamydomonas requires 2', 3'-cyclic phosphate and 5'-phosphate ends for ligation to form a 2'-phosphomonoester, 3',5'-phosphodiester bond. Using...