K Pfizenmaier
Overview
Explore the profile of K Pfizenmaier including associated specialties, affiliations and a list of published articles.
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Articles
156
Citations
3909
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Recent Articles
1.
Siegemund M, Pollak N, Seifert O, Wahl K, Hanak K, Vogel A, et al.
Cell Death Dis
. 2012 Apr;
3:e295.
PMID: 22495350
Although targeting of the death receptors (DRs) DR4 and DR5 still appears a suitable antitumoral strategy, the limited clinical responses to recombinant soluble TNF-related apoptosis inducing ligand (TRAIL) necessitate novel...
2.
Pfizenmaier K, Jung H, Kurrle R, Rollinghoff M, Wagner H
Immunogenetics
. 2012 Mar;
10(4):395-404.
PMID: 22457931
Herpes-simplex-virus (HSV) specific, H-2k-restricted, immune cytotoxic T lymphocytes also lyse noninfected H-2d target cells. Genetic mapping studies revealed that HSV-specific Dk-restricted CTL cross-react with allogeneic targets expressing Dd alloantigens. Cold...
3.
Schneider B, Munkel S, Krippner-Heidenreich A, Grunwald I, Wels W, Wajant H, et al.
Cell Death Dis
. 2011 Mar;
1:e68.
PMID: 21364672
In an attempt to improve TRAIL's (tumor necrosis factor-related apoptosis-inducing ligand) tumor selective activity a variant was designed, in which the three TRAIL protomers are expressed as a single polypeptide...
4.
Chertoff M, Di Paolo N, Schoeneberg A, Depino A, Ferrari C, Wurst W, et al.
Exp Neurol
. 2010 Nov;
227(2):237-51.
PMID: 21093436
Tumor necrosis factor (TNF)-α, a pro-inflammatory cytokine, has been implicated in both neuronal death and survival in Parkinson's disease (PD). The substantia nigra (SN), a CNS region affected in PD,...
5.
Berg D, Lehne M, Muller N, Siegmund D, Munkel S, Sebald W, et al.
Cell Death Differ
. 2007 Aug;
14(12):2021-34.
PMID: 17703232
Variants of human TRAIL (hTRAIL) and human CD95L (hCD95L), encompassing the TNF homology domain (THD), interact with the corresponding receptors and stimulate CD95 and TRAILR2 signaling after cross-linking. The murine...
6.
Watermann I, Gerspach J, Lehne M, Seufert J, Schneider B, Pfizenmaier K, et al.
Cell Death Differ
. 2006 Oct;
14(4):765-74.
PMID: 17053806
To achieve tumor cell-restricted activation of CD95, we developed a CD95L fusion protein format, in which CD95L activity is only unmasked upon antibody-mediated binding to tumor cells and subsequent processing...
7.
Gerspach J, Muller D, Munkel S, Selchow O, Nemeth J, Noack M, et al.
Cell Death Differ
. 2005 Jul;
13(2):273-84.
PMID: 16052236
Tumor necrosis factor (TNF) prodrugs are fusion proteins comprised of an N-terminal single-chain antibody variable fragment (scFv) targeting a TNF effector and a C-terminal TNF receptor (TNFR)1-derived inhibitor module. Introduction...
8.
Wajant H, Pfizenmaier K, Scheurich P
Cell Death Differ
. 2003 Mar;
10(1):45-65.
PMID: 12655295
A single mouse click on the topic tumor necrosis factor (TNF) in PubMed reveals about 50,000 articles providing one or the other information about this pleiotropic cytokine or its relatives....
9.
Wajant H, Pfizenmaier K, Scheurich P
Apoptosis
. 2002 Sep;
7(5):449-59.
PMID: 12207178
TNF-related apoptosis-inducing ligand (TRAIL/APO-2L) is a typical member of the TNF ligand family that induces apoptosis by activating the death receptors TRAIL-R1 and TRAIL-R2. TRAIL has attracted great attention in...
10.
Brocks B, Garin-Chesa P, Behrle E, Park J, Rettig W, Pfizenmaier K, et al.
Mol Med
. 2001 Oct;
7(7):461-9.
PMID: 11683371
Background: Fibroblast activation protein (FAP) is a type II membrane protein expressed on tumor stroma fibroblasts in more than 90% of all carcinomas. FAP serves as a diagnostic marker and...