K N Rothblum
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Explore the profile of K N Rothblum including associated specialties, affiliations and a list of published articles.
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12
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389
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Recent Articles
1.
Dostal D, Rothblum K, Baker K
Anal Biochem
. 1994 Dec;
223(2):239-50.
PMID: 7887470
We have developed a multiplex, competitive, reverse-transcriptase polymerase chain reaction (RT-PCR) method which measures absolute levels of renin, angiotensinogen, and the housekeeping transcript elongation factor-1 alpha (EF-1 alpha) mRNA. Sample...
2.
Dostal D, Rothblum K, Chernin M, COOPER G, Baker K
Am J Physiol
. 1992 Oct;
263(4 Pt 1):C838-50.
PMID: 1415670
There is increasing evidence that the renin-angiotensin system (RAS) modulates cardiovascular function through both blood-borne and tissue-derived components. The existence of a local RAS has been proposed in the heart...
3.
Dostal D, Rothblum K, Conrad K, COOPER G, Baker K
Am J Physiol
. 1992 Oct;
263(4 Pt 1):C851-63.
PMID: 1384355
Angiotensin II (ANG II) is a stimulus for positive chronotropic and inotropic effects, protein synthesis, and hypertrophic growth in cardiac tissue. These short- and long-term effects of ANG II are...
4.
Knoll B, Rothblum K, Longley M
J Biol Chem
. 1988 Aug;
263(24):12020-7.
PMID: 3042787
Three closely related alkaline phosphatase (ALP) genes reside on the long arm of chromosome 2 in man. One of these genes (the placental ALP-1) encodes the classic heat-stable placental alkaline...
5.
Knoll B, Rothblum K, Longley M
Gene
. 1987 Jan;
60(2-3):267-76.
PMID: 3443302
There are at least three alkaline phosphatase (AP) isoenzymes in man: a heat-stable placental enzyme (PLAP), a less heat-stable intestinal form (IAP), and the very heat-labile AP enriched in liver,...
6.
Henthorn P, Knoll B, Raducha M, Rothblum K, Slaughter C, Weiss M, et al.
Proc Natl Acad Sci U S A
. 1986 Aug;
83(15):5597-601.
PMID: 3461452
Amino-terminal amino acid sequences (42 residues) were determined for the products of the three common alleles at the human placental alkaline phosphatase [orthophosphoric-monoester phosphohydrolase (alkaline optimum), EC 3.1.3.1] gene locus....
7.
Stone E, Rothblum K, Alevy M, Kuo T, Schwartz R
Proc Natl Acad Sci U S A
. 1985 Mar;
82(6):1628-32.
PMID: 3856841
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), an evolutionarily conserved glycolytic enzyme, is constitutively expressed in most cell types yet is induced to high levels during the development of fast twitch muscle fibers. To...
8.
Chang K, Rothblum K, Schwartz R
Nucleic Acids Res
. 1985 Feb;
13(4):1223-37.
PMID: 3855241
We sequenced the entire chicken alpha-cardiac actin gene. A single intron was positioned 20 bp upstream from the initiation ATG codon in the 5' non-coding region while the coding region...
9.
Stone E, Rothblum K, Schwartz R
Nature
. 1985 Feb;
313(6002):498-500.
PMID: 3969156
The function of introns in the evolution of genes can be explained in at least two ways: either introns appeared late in evolution and therefore could not have participated in...
10.
Dugaiczyk A, Haron J, Stone E, Dennison O, Rothblum K, Schwartz R
Biochemistry
. 1983 Mar;
22(7):1605-13.
PMID: 6303388
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was purified from the breast muscles of 3-week-old chickens and used to raise a specific antiserum in rabbits. This antiserum was coupled to an in vitro translation...