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K McCorkle

Explore the profile of K McCorkle including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 225
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Recent Articles
1.
Higa M, Kakuma T, Pan W, Wang Z, Babcock E, McCorkle K, et al.
Biochem Biophys Res Commun . 2001 Feb; 279(3):786-91. PMID: 11162429
In normal rats, adenovirus-induced hyperleptinemia causes disappearance of visible body fat, downregulation of lipogenic enzymes, and upregulation of oxidative enzymes and thermogenic proteins. In addition, preadipocyte markers replace mature adipocyte...
2.
Lee Y, Wang M, Kakuma T, Wang Z, Babcock E, McCorkle K, et al.
J Biol Chem . 2000 Nov; 276(8):5629-35. PMID: 11096093
To test the hypothesis that the physiologic liporegulatory role of hyperleptinemia is to prevent steatosis during caloric excess, we induced obesity by feeding normal Harlan Sprague-Dawley rats a 60% fat...
3.
Pieber T, Stein D, Ogawa A, Alam T, Ohneda M, McCorkle K, et al.
Am J Physiol . 1993 Sep; 265(3 Pt 1):E446-53. PMID: 8105694
To determine if increased secretion of amylin can be implicated in the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM) in vitro and in vivo, we studied its relationships to insulin in...
4.
Johnson J, Crider B, McCorkle K, Alford M, Unger R
N Engl J Med . 1990 Mar; 322(10):653-9. PMID: 2406597
Because glucose-stimulated insulin secretion is selectively impaired during the development of insulin-dependent diabetes mellitus (IDDM), we tested the possibility that the glucose transporter of pancreatic islet beta cells is a...
5.
Chen L, Komiya I, Inman L, McCorkle K, Alam T, Unger R
Proc Natl Acad Sci U S A . 1989 Feb; 86(4):1367-71. PMID: 2645581
We have evaluated in situ hybridization histochemistry as a means of estimating simultaneously the level of prohormone mRNA and the dimensions of rat pancreatic islets. Localization of the 27-mer 32P-labeled...
6.
Tominaga M, Komiya I, Johnson J, Inman L, Alam T, Moltz J, et al.
Proc Natl Acad Sci U S A . 1986 Dec; 83(24):9749-53. PMID: 3540950
The insulin and glucagon responses to 10 mM glucose and 10 mM arginine were studied in pancreata isolated from nondiabetic diabetes-prone and diabetes-resistant BB/W rats at 60, 80, and 140...
7.
Wasada T, McCorkle K, Harris V, Kawai K, Howard B, Unger R
J Clin Invest . 1981 Oct; 68(4):1106-7. PMID: 7287903
To determine whether gastric inhibitory polypeptide (GIP) promotes the clearance of chylomicron triglycerides (TG) from the circulation in dogs, chyle collected from donor dogs via a thoracic duct fistula was...
8.
Wasada T, Howard B, McCorkle K, Harris V, Unger R
Diabetes . 1981 Apr; 30(4):358-61. PMID: 6110603
High plasma levels of free fatty acids (FFA) stimulate the secretion of splanchnic somatostatin, and both are elevated in insulin deficiency. To determine if the hypersomatostatinemia of insulin deficiency is...
9.
Harris V, Conlon J, Srikant C, McCorkle K, Schusdziarra V, Ipp E, et al.
Clin Chim Acta . 1978 Jul; 87(2):275-83. PMID: 657552
No abstract available.
10.
Srikant C, Freeman D, McCorkle K, Unger R
J Biol Chem . 1977 Nov; 252(21):7434-8. PMID: 914819
Glucagon binding by liver cell membranes was examined in rats with chronically elevated plasma levels of immunoreactive glucagon (IRG) resulting from insulin deficiency, starvation, or twice daily glucagon injections. The...