K M Lerea
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Explore the profile of K M Lerea including associated specialties, affiliations and a list of published articles.
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25
Citations
302
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Recent Articles
1.
Jiang H, Zhu A, Mamczur M, Falck J, Lerea K, McGiff J
Br J Pharmacol
. 2007 Jun;
151(7):1033-40.
PMID: 17558440
Background And Purpose: Red blood cells (RBCs) are reservoirs of vasodilatory, antiaggregatory, and antiinflammatory lipid mediators-epoxyeicosatrienoic acids (EETs). This study addresses the formation and release of erythrocyte-derived EETs in response...
2.
Ali S, Wei Y, Lerea K, Becker L, Rubin C, Wang W
Cell Physiol Biochem
. 2001 Jun;
11(3):135-42.
PMID: 11410709
We have used the patch-clamp technique to explore the role of A Kinase Anchor Proteins (AKAP) in mediating the effect of cAMP on ROMK1 channels expressed in the Xenopus oocytes....
3.
Bruder J, Hsieh T, Lerea K, Olson S, Wu J
BMC Cell Biol
. 2001 Feb;
2:1.
PMID: 11178103
Background: Atherosclerosis and coronary heart disease (CHD) are significant contributors to morbidity and mortality in developed countries. A noted exception is the low mortality of CHD in France, particularly the...
4.
Kirk R, Deitch J, Wu J, Lerea K
Blood Cells Mol Dis
. 2000 Sep;
26(2):144-50.
PMID: 11001623
Resveratrol, a polyphenolic compound found in red wines, is believed to be a contributor in decreasing the incidence of coronary heart disease. Although its primary target is unknown, it blocks...
5.
Kirk R, Sanderson M, Lerea K
J Biol Chem
. 2000 Jul;
275(40):30901-6.
PMID: 10896934
The mechanism of outside-in signaling by integrins parallels that for growth factor receptors. In both pathways, phosphorylation of a cytoplasmic segment on tyrosine generates a docking site for proteins containing...
6.
Wang W, Lerea K, Chan M, Giebisch G
Am J Physiol Renal Physiol
. 2000 Feb;
278(1):F165-71.
PMID: 10644668
The apical small conductance (SK) channel plays a key role in K secretion in the cortical collecting duct (CCD). A high-K intake stimulates renal K secretion and involves a significant...
7.
Lerea K, Cordero K, Sakariassen K, Kirk R, Fried V
J Biol Chem
. 1999 Jan;
274(4):1914-9.
PMID: 9890945
Protein seryl/threonyl phosphatase inhibitors such as calyculin A block inside-out and outside-in platelet signaling. Our studies demonstrate that the addition of calyculin A blocks platelet adhesion and spreading on fibrinogen,...
8.
Ali S, Chen X, Lu M, Xu J, Lerea K, Hebert S, et al.
Proc Natl Acad Sci U S A
. 1998 Aug;
95(17):10274-8.
PMID: 9707637
In the present study, we have used the two-electrode voltage-clamp and patch-clamp techniques to study the effects of forskolin and cAMP on the ROMK1 channels, which are believed to be...
9.
Li N, Lerea K, Etlinger J
Biochem Biophys Res Commun
. 1996 Aug;
225(3):855-60.
PMID: 8780702
PA28, also referred to as 11S regulator, is a potent activator of the peptidase activities of the proteasome (multicatalytic proteinase complex). Although the role(s) of PA28-20S proteasome complexes in cellular...
10.
Zhang Q, Carr D, Lerea K, Scott J, Newman S
Dev Biol
. 1996 May;
176(1):51-61.
PMID: 8654894
Differentiation of chicken limb cartilage is accompanied by a rise in intracellular cyclic AMP, an inducer of cartilage-specific gene expression. A basic approximately 35-kDa protein, designated p35, is the major...