K M Druey
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Explore the profile of K M Druey including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
579
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0
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Recent Articles
1.
Ma M, Redes J, Percopo C, Druey K, Rosenberg H
Clin Exp Allergy
. 2018 Feb;
48(6):691-702.
PMID: 29473965
Background: Eosinophils in the nasal mucosa are an elemental feature of allergic rhinitis. Objective: Our objective was to explore eosinophilic inflammation and its impact on respiratory virus infection at the...
2.
Druey K
Sci STKE
. 2001 Oct;
2001(104):re14.
PMID: 11604548
The regulators of heterotrimeric guanosine triphosphate (GTP)-binding protein (G protein) signaling (RGS proteins) were named for their ability to act as GTP-activating proteins (GAPs) for G proteins and, thus, limit...
3.
Derrien A, Druey K
J Biol Chem
. 2001 Oct;
276(51):48532-8.
PMID: 11602604
Galpha(i)-coupled receptor stimulation results in epidermal growth factor receptor (EGFR) phosphorylation and MAPK activation. Regulators of G protein signaling (RGS proteins) inhibit G protein-dependent signal transduction by accelerating Galpha(i) GTP...
4.
Sullivan B, Marshansky V, Lin H, Kehrl J, Ausiello D, Brown D, et al.
Mol Biol Cell
. 2000 Sep;
11(9):3155-68.
PMID: 10982407
COPI, a protein complex consisting of coatomer and the small GTPase ARF1, is an integral component of some intracellular transport carriers. The association of COPI with secretory membranes has been...
5.
Cavalli A, Druey K, Milligan G
J Biol Chem
. 2000 May;
275(31):23693-9.
PMID: 10807934
Agonist-stimulated high affinity GTPase activity of fusion proteins between the alpha(2A)-adrenoreceptor and the alpha subunits of forms of the G proteins G(i1), G(i2), G(i3), and G(o1), modified to render them...
6.
Moratz C, Kang V, Druey K, Shi C, Scheschonka A, Murphy P, et al.
J Immunol
. 2000 Feb;
164(4):1829-38.
PMID: 10657631
Regulator of G protein signaling (RGS) proteins modulate signaling through pathways that use heterotrimeric G proteins as transducing elements. RGS1 is expressed at high levels in certain B cell lines...
7.
Druey K, Ugur O, Caron J, Chen C, Backlund P, Jones T
J Biol Chem
. 1999 Jun;
274(26):18836-42.
PMID: 10373502
RGS proteins (Regulators of G protein Signaling) are a recently discovered family of proteins that accelerate the GTPase activity of heterotrimeric G protein alpha subunits of the i, q, and...
8.
Beadling C, Druey K, Richter G, Kehrl J, Smith K
J Immunol
. 1999 Mar;
162(5):2677-82.
PMID: 10072511
The newly recognized regulators of G protein signaling (RGS) attenuate heterotrimeric G protein signaling pathways. We have cloned an IL-2-induced gene from human T cells, cytokine-responsive gene 1, which encodes...
9.
Bowman E, Campbell J, Druey K, Scheschonka A, Kehrl J, Butcher E
J Biol Chem
. 1998 Oct;
273(43):28040-8.
PMID: 9774420
Serpentine Galphai-linked receptors support rapid adhesion and directed migration of leukocytes and other cell types. The intracellular mechanisms mediating and regulating chemoattractant-directed adhesion and locomotion are only now beginning to...
10.
Druey K, Sullivan B, Brown D, Fischer E, Watson N, Blumer K, et al.
J Biol Chem
. 1998 Jul;
273(29):18405-10.
PMID: 9660808
The members of a recently identified protein family termed regulators of G-protein signaling (RGS) act as GTPase-activating proteins for certain Galpha subunits in vitro, but their physiological effects in cells...