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E C Butcher

Explore the profile of E C Butcher including associated specialties, affiliations and a list of published articles. Areas
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Articles 232
Citations 14658
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Recent Articles
1.
Zeng R, Bscheider M, Lahl K, Lee M, Butcher E
Mucosal Immunol . 2015 Jul; 9(1):183-93. PMID: 26129652
The vitamin A metabolite retinoic acid (RA) regulates adaptive immunity in the intestines, with well-characterized effects on IgA responses, Treg induction, and gut trafficking of T- and B-effector cells. It...
2.
Zeng R, Oderup C, Yuan R, Lee M, Habtezion A, Hadeiba H, et al.
Mucosal Immunol . 2012 Dec; 6(4):847-56. PMID: 23235743
The vitamin A metabolite retinoic acid (RA) regulates intestinal immune responses through immunomodulatory actions on intestinal dendritic cells (DCs) and lymphocytes. Here, we show that RA also controls the generation...
3.
Skrzeczynska-Moncznik J, Wawro K, Stefanska A, Oleszycka E, Kulig P, Zabel B, et al.
Biochem Biophys Res Commun . 2009 Jan; 380(2):323-7. PMID: 19168032
Interferon alpha-producing plasmacytoid dendritic cells (pDC) are crucial contributors to pro-inflammatory or tolerogenic immune responses and are important in autoimmune diseases such as psoriasis. pDC accumulate in the lesional skin...
4.
Butcher E
Ernst Schering Res Found Workshop . 2007 Jan; (61):153-72. PMID: 17249501
The focus of innovation in current drug discovery is on new targets, yet compound efficacy and safety in biological models of disease, not target selection, qualify drug candidates for the...
5.
Reiss Y, Proudfoot A, Power C, Campbell J, Butcher E
J Exp Med . 2001 Nov; 194(10):1541-7. PMID: 11714760
The chemokine thymus and activation-regulated chemokine (TARC; CCL17) is displayed by cutaneous (but not intestinal) venules, and is thought to trigger vascular arrest of circulating skin homing memory T cells,...
6.
Kim C, ROTT L, Kunkel E, Genovese M, Andrew D, Wu L, et al.
J Clin Invest . 2001 Nov; 108(9):1331-9. PMID: 11696578
Current concepts of chemokine receptor (CKR) association with Th1 and Th2 cell polarization and effector function have largely ignored the diverse nature of effector and memory T cells in vivo....
7.
Salmi M, Alanen K, Grenman S, Briskin M, Butcher E, Jalkanen S
Gastroenterology . 2001 Oct; 121(4):853-64. PMID: 11606499
Background & Aims: In adults, binding of mucosal addressin cell adhesion molecule 1 (MAdCAM-1) to lymphocyte alpha4beta7 integrin directs cell trafficking to gut, whereas interaction of peripheral node addressins (PNAd)...
8.
Kim C, Campbell D, Butcher E
Trends Immunol . 2001 Sep; 22(10):527-30. PMID: 11574259
No abstract available.
9.
Campbell D, Kim C, Butcher E
Nat Immunol . 2001 Aug; 2(9):876-81. PMID: 11526405
We identified specialized B helper and tissue inflammatory CD4(+) T cell subsets that developed concurrently from common naïve precursors during the primary immune response. These separable populations were distinguishable by...
10.
Kim C, Rott L, Clark-Lewis I, Campbell D, Wu L, Butcher E
J Exp Med . 2001 Jun; 193(12):1373-81. PMID: 11413192
The T helper (Th) cell pool is composed of specialized cells with heterogeneous effector functions. Apart from Th1 and 2 cells, CXCR5+ T cells have been suggested to be another...