K L Skorecki
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Explore the profile of K L Skorecki including associated specialties, affiliations and a list of published articles.
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62
Citations
588
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Recent Articles
1.
Assady S, Maor G, Amit M, Itskovitz-Eldor J, Skorecki K, Tzukerman M
Diabetes
. 2001 Jul;
50(8):1691-7.
PMID: 11473026
Type 1 diabetes generally results from autoimmune destruction of pancreatic islet beta-cells, with consequent absolute insulin deficiency and complete dependence on exogenous insulin treatment. The relative paucity of donations for...
2.
Braunstein I, Cohen-Barak O, Shachaf C, Ravel Y, Mills G, Tzukerman M, et al.
Cancer Res
. 2001 Jul;
61(14):5529-36.
PMID: 11454703
The telomerase RNA-protein complex responsible for maintenance of telomeric DNA at chromosome ends, is usually inactive in most primary somatic human cells, but is specifically activated with in vitro immortalization...
3.
Tzukerman M, Shachaf C, Ravel Y, Braunstein I, Cohen-Barak O, Skorecki K
Mol Biol Cell
. 2000 Dec;
11(12):4381-91.
PMID: 11102531
Three different cell differentiation experimental model systems (human embryonic stem cells, mouse F9 cells, and human HL-60 promyelocytic cells) were used to determine the relationship between the reduction in telomerase...
4.
Shachaf C, Skorecki K, Tzukerman M
Am J Physiol Renal Physiol
. 2000 Mar;
278(3):F406-16.
PMID: 10710545
Expression of the Npt2 gene, encoding the type II sodium-dependent phosphate cotransporter, is restricted to renal proximal tubule epithelium. We have isolated a 4,740-bp fragment of the 5'-flanking sequence of...
5.
Ofir R, Wong A, McDermid H, Skorecki K, Selig S
Proc Natl Acad Sci U S A
. 1999 Sep;
96(20):11434-9.
PMID: 10500194
Telomeres are distinct structures, composed of short, repeated sequences, at the ends of all eukaryotic chromosomes. Telomeres have been shown in yeast to induce late replication in S phase and...
6.
Mucsi I, Skorecki K, Goldberg H
J Biol Chem
. 1996 Jul;
271(28):16567-72.
PMID: 8663331
The kinases and regulatory proteins that convey signals initiated by transforming growth factor-beta (TGF-beta) to the nucleus are poorly characterized. To study the role of the extracellular signal-regulated kinase (ERK)...
7.
Miller J, Floras J, Zinman B, Skorecki K, Logan A
Clin Sci (Lond)
. 1996 Mar;
90(3):189-95.
PMID: 8777824
1. In insulin-dependent diabetes mellitus, hyperglycaemia has a profound effect on renal and systemic haemodynamic function. The mechanism for this is unknown. 2. We conducted a study in 11 males...
8.
Hack N, Tay A, Schultz A, Muzin N, Clayman P, Egan S, et al.
Clin Exp Pharmacol Physiol
. 1996 Jan;
23(1):71-5.
PMID: 8713499
1. The precursor of eicosanoids is arachidonic acid, which emanates from the cleavage of the sn-2 position of phospholipids by phospholipase A2 (PLA2). Eicosanoids have diverse physiological and pathophysiological effects...
9.
Tobe S, Noble-Topham S, Andrulis I, Hartwick R, Skorecki K, Warner E
Clin Cancer Res
. 1995 Dec;
1(12):1611-5.
PMID: 9815963
Levels of mRNA expressed by the multidrug resistance gene MDR1 were examined in 23 renal cell carcinoma samples and adjacent normal kidney cortex using reverse-transcription PCR. Comparison of MDR1 levels...
10.
Hack N, Schultz A, Clayman P, Goldberg H, Skorecki K
Pediatr Nephrol
. 1995 Aug;
9(4):514-25.
PMID: 7577422
Transmembrane signal transduction is the process whereby a ligand binds to the external surface of the cell membrane and elicits a physiological response specific for that ligand and cell type....