K L Hartshorn
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Explore the profile of K L Hartshorn including associated specialties, affiliations and a list of published articles.
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48
Citations
1367
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Recent Articles
1.
Hartshorn K, White M, Smith K, Sorensen G, Kuroki Y, Holmskov U, et al.
Scand J Immunol
. 2010 Jul;
72(1):22-30.
PMID: 20591072
Collectins contribute to host defence through interactions with glycoconjugates on pathogen surfaces. We have prepared recombinant trimeric neck and carbohydrate recognition domains (NCRD) of collectins, and we now show that...
2.
White M, Helmerhorst E, Ligtenberg A, Karpel M, Tecle T, Siqueira W, et al.
Oral Microbiol Immunol
. 2009 Jan;
24(1):18-24.
PMID: 19121065
Introduction: Saliva is a potentially important barrier against respiratory viral infection but its mechanism of action is not well studied. Methods: We tested the antiviral activities of whole saliva, specific...
3.
Tecle T, White M, Crouch E, Hartshorn K
Arch Virol
. 2007 May;
152(9):1731-42.
PMID: 17514488
The collectins, lung surfactant proteins A and D (SP-A and SP-D), contribute to innate host defense against influenza A virus (IAV) in vivo. Although collectins bind to the viral hemagglutinin...
4.
Lee R, White M, Hartshorn K
Scand J Immunol
. 2006 Feb;
63(2):81-9.
PMID: 16476006
Neutrophils are involved in the initial host response to influenza A virus (IAV) infection and exhibit both activation and depressed function after exposure to the virus. We demonstrate that IAV...
5.
Engelich G, Wright D, Hartshorn K
Clin Infect Dis
. 2001 Nov;
33(12):2040-8.
PMID: 11698988
There is evidence that acquired dysfunction of neutrophils, monocytes, or macrophages is an important cause of infection in patients with diabetes mellitus, renal or hepatic failure, alcoholism, autoimmune diseases, influenza...
6.
Levine A, Whitsett J, Hartshorn K, Crouch E, Korfhagen T
J Immunol
. 2001 Nov;
167(10):5868-73.
PMID: 11698462
Mice lacking surfactant protein surfactant protein D (SP-D(-/-)) and wild-type mice (SP-D(+/+)) were infected with influenza A virus (IAV) by intranasal instillation. IAV infection increased the endogenous SP-D concentration in...
7.
White M, Crouch E, Chang D, Hartshorn K
Biochem Biophys Res Commun
. 2001 Aug;
286(1):206-13.
PMID: 11485330
Altering the carbohydrate binding properties of surfactant protein D (SP-D) [e.g., by replacing its carbohydrate recognition domain (CRD) with that of either mannose binding lectin (MBL) or conglutinin] can increase...
8.
Choufani E, Lazar H, Hartshorn K
J Clin Oncol
. 2001 Aug;
19(15):3574-5.
PMID: 11481366
No abstract available.
9.
Kandel R, Hartshorn K
BioDrugs
. 2001 Jul;
15(5):303-23.
PMID: 11437694
Influenza virus infections remain an important cause of morbidity and mortality. Furthermore, a recurrence of pandemic influenza remains a real possibility. There are now effective ways to both prevent and...
10.
Engelich G, White M, Hartshorn K
J Leukoc Biol
. 2001 Feb;
69(1):50-6.
PMID: 11200067
Bacterial superinfections are an important cause of morbidity and mortality during influenza A virus (IAV) epidemics. We demonstrate that incubation with the combination of IAV and Streptococcus pneumoniae caused marked...