E C Crouch
Overview
Explore the profile of E C Crouch including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
1583
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Recent Articles
1.
Hartshorn K, White M, Smith K, Sorensen G, Kuroki Y, Holmskov U, et al.
Scand J Immunol
. 2010 Jul;
72(1):22-30.
PMID: 20591072
Collectins contribute to host defence through interactions with glycoconjugates on pathogen surfaces. We have prepared recombinant trimeric neck and carbohydrate recognition domains (NCRD) of collectins, and we now show that...
2.
Tecle T, White M, Crouch E, Hartshorn K
Arch Virol
. 2007 May;
152(9):1731-42.
PMID: 17514488
The collectins, lung surfactant proteins A and D (SP-A and SP-D), contribute to innate host defense against influenza A virus (IAV) in vivo. Although collectins bind to the viral hemagglutinin...
3.
Levine A, Whitsett J, Hartshorn K, Crouch E, Korfhagen T
J Immunol
. 2001 Nov;
167(10):5868-73.
PMID: 11698462
Mice lacking surfactant protein surfactant protein D (SP-D(-/-)) and wild-type mice (SP-D(+/+)) were infected with influenza A virus (IAV) by intranasal instillation. IAV infection increased the endogenous SP-D concentration in...
4.
Crouch E
Respir Res
. 2001 Oct;
1(2):93-108.
PMID: 11667972
Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is synthesized and secreted by...
5.
Trask B, Malone M, Lum E, Welgus H, Crouch E, Shapiro S
J Biol Chem
. 2001 Aug;
276(41):37846-52.
PMID: 11481321
Recent studies strongly suggest that surfactant protein D (SP-D) plays important roles in pulmonary host defense and the regulation of immune and inflammatory reactions in the lung. Although SP-D can...
6.
Standing J, Crouch E, Limper A
Am J Respir Cell Mol Biol
. 2001 Apr;
24(4):475-84.
PMID: 11306442
Pneumocystis carinii continues to cause severe pneumonia in immunocompromised patients. Surfactant protein D (SP-D), a lung collectin, markedly accumulates during P. carinii pneumonia and binds to glycoprotein A (gpA) on...
7.
Zhang L, Ikegami M, Crouch E, Korfhagen T, Whitsett J
J Biol Chem
. 2001 Mar;
276(22):19214-9.
PMID: 11278637
Pulmonary surfactant protein-D (SP-D) is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung. SP-D is assembled...
8.
Hartshorn K, White M, Voelker D, Coburn J, Zaner K, Crouch E
Biochem J
. 2000 Oct;
351 Pt 2:449-58.
PMID: 11023831
Collectins are important in the initial containment of a variety of pathogens, including influenza A virus (IAV). We provide the first systematic evaluation of the oligosaccharide-binding sites for pulmonary surfactant...
9.
He Y, Crouch E, Rust K, Spaite E, Brody S
J Biol Chem
. 2000 Aug;
275(40):31051-60.
PMID: 10915785
Surfactant protein D (SP-D) plays roles in pulmonary host defense and surfactant homeostasis and is increased following lung injury. Because AP-1 proteins regulate cellular responses to diverse environmental stimuli, we...
10.
Hartshorn K, Sastry K, Chang D, White M, Crouch E
Am J Physiol Lung Cell Mol Physiol
. 2000 Jan;
278(1):L90-8.
PMID: 10645895
We previously demonstrated that bovine serum conglutinin has markedly greater ability to inhibit influenza A virus (IAV) infectivity than other collectins. We now show that recombinant conglutinin and a chimeric...