K Higashio
Overview
Explore the profile of K Higashio including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
64
Citations
3505
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yano K, Nakagawa N, Yasuda H, Tsuda E, Higashio K
J Bone Miner Metab
. 2001 Oct;
19(6):365-72.
PMID: 11685652
To understand the involvement of osteoclastogenesis inhibitory factor (OCIF), also called osteoprotegerin (OPG), in the pathogenesis of bone destruction in rheumatoid arthritis (RA), we investigated the cytokine network involved in...
2.
Yano K, Shibata O, Mizuno A, Kobayashi F, Higashio K, Morinaga T, et al.
Biochem Biophys Res Commun
. 2001 Oct;
288(1):217-24.
PMID: 11594776
Osteoprotegerin (OPG)/osteoclastogenesis inhibitory factor (OCIF) is a soluble member of the tumor necrosis factor receptor family and plays a crucial role in the negative regulation of osteoclastic bone resorption. We...
3.
Quinn J, Itoh K, Udagawa N, Hausler K, Yasuda H, Shima N, et al.
J Bone Miner Res
. 2001 Oct;
16(10):1787-94.
PMID: 11585342
Transforming growth factor beta (TGF-beta) is abundant in bone and has complex effects on osteolysis, with both positive and negative effects on osteoclast differentiation, suggesting that it acts via more...
4.
Itoh K, Udagawa N, Katagiri T, Iemura S, Ueno N, Yasuda H, et al.
Endocrinology
. 2001 Jul;
142(8):3656-62.
PMID: 11459815
Bone is a major storage site for TGFbeta superfamily members, including TGFbeta and bone morphogenetic proteins. It is believed that these cytokines are released from bone during bone resorption. Recent...
5.
Ihara H, Denhardt D, Furuya K, Yamashita T, Muguruma Y, Tsuji K, et al.
J Biol Chem
. 2001 Mar;
276(16):13065-71.
PMID: 11278791
Osteopontin is an RGDS-containing protein that acts as a ligand for the alpha(v)beta(3) integrin, which is abundantly expressed in osteoclasts, cells responsible for bone resorption in osteopenic diseases such as...
6.
Oh S, Miyazaki M, Kouchi H, Inoue Y, Sakaguchi M, Tsuji T, et al.
Biochem Biophys Res Commun
. 2000 Dec;
279(2):500-4.
PMID: 11118315
Bone marrow (BM) cells originally include alpha-fetoprotein (AFP)- and c-Met [a receptor for hepatocyte growth factor (HGF)]-expressing cells. In vitro treatment of BM cells with HGF induced albumin-expressing hepatocyte-like cells....
7.
Shiota A, Yamashita Y, Fujise N, Masunaga H, Yasuda H, Higashio K
Pharmacol Res
. 2000 Oct;
42(5):443-52.
PMID: 11023706
Here we report the effect of the recombinant human deleted form of hepatocyte growth factor (dHGF) on lipid metabolism in rats. In primary cultured rat hepatocytes, dHGF accelerated incorporation of...
8.
Udagawa N, Takahashi N, Yasuda H, Mizuno A, Itoh K, Ueno Y, et al.
Endocrinology
. 2000 Aug;
141(9):3478-84.
PMID: 10965921
Osteoprotegerin (OPG), a soluble decoy receptor for receptor activator of nuclear factor-kappaB ligand (RANKL)/osteoclast differentiation factor, inhibits both differentiation and function of osteoclasts. We previously reported that OPG-deficient mice exhibited...
9.
Kobayashi K, Takahashi N, Jimi E, Udagawa N, Takami M, Kotake S, et al.
J Exp Med
. 2000 Jan;
191(2):275-86.
PMID: 10637272
Osteoclast differentiation factor (ODF, also called RANKL/TRANCE/OPGL) stimulates the differentiation of osteoclast progenitors of the monocyte/macrophage lineage into osteoclasts in the presence of macrophage colony-stimulating factor (M-CSF, also called CSF-1)....
10.
Udagawa N, Takahashi N, Jimi E, Matsuzaki K, Tsurukai T, Itoh K, et al.
Bone
. 1999 Nov;
25(5):517-23.
PMID: 10574571
We previously reported that osteoblasts/stromal cells are essentially involved in the activation as well as differentiation of osteoclasts through a mechanism involving cell-to-cell contact between osteoblasts/stromal cells and osteoclast precursors/osteoclasts....