K H Pearce Jr
Overview
Explore the profile of K H Pearce Jr including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
77
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Recent Articles
1.
Sossong Jr T, HENSLEY P, Pearce Jr K
Biochemistry
. 1999 Nov;
38(45):14843-50.
PMID: 10555966
The essential bacterial cell division protein FtsZ (filamentation temperature-sensitive protein Z) is a distant homologue to the eukaryotic cytoskeletal protein tubulin. We have examined the GTP hydrolytic activity of Escherichia...
2.
Pearce Jr K, Cunningham B, Fuh G, Teeri T, Wells J
Biochemistry
. 1999 Jan;
38(1):81-9.
PMID: 9890885
The human growth hormone (hGH)-receptor interaction was used to study the relationship between hormone-receptor affinity and bioactivity. hGH has two nonequivalent sites, called site 1 and site 2, that bind...
3.
Mutational analysis of thrombopoietin for identification of receptor and neutralizing antibody sites
Pearce Jr K, Potts B, Presta L, Bald L, Fendly B, Wells J
J Biol Chem
. 1997 Aug;
272(33):20595-602.
PMID: 9252374
Thrombopoietin (TPO) is a hematopoietin important for megakaryocyte proliferation and production of blood platelets. We sought to characterize how TPO binds and activates its receptor, myeloproliferative leukemia virus receptor. The...
4.
Pearce Jr K, Ultsch M, Kelley R, de Vos A, Wells J
Biochemistry
. 1996 Aug;
35(32):10300-7.
PMID: 8756685
Mutational studies have shown that over two-thirds of the contact side chains at the human growth hormone (hGH)-receptor interface have little or no impact on binding affinity when converted to...