K F Kozarsky
Overview
Explore the profile of K F Kozarsky including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
28
Citations
1028
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kozarsky K, Wilson J
Trends Cardiovasc Med
. 2011 Jan;
5(5):205-9.
PMID: 21232261
Gene therapy in its simplest form is the treatment of genetic disease by the introduction of normal (nondefective) genes. In several hypercholesterolemic disorders, the defective genes have been identified, and...
2.
Wadsack C, Hammer A, Levak-Frank S, Desoye G, Kozarsky K, Hirschmugl B, et al.
Placenta
. 2003 Feb;
24(2-3):131-43.
PMID: 12566239
As villous trophoblast does represent the contact zone between foetal and maternal tissues, the present in vitro study was aimed at investigating cholesterol supply from human high density lipoprotein subclass...
3.
Kozarsky K
Curr Opin Pharmacol
. 2001 Nov;
1(2):197-202.
PMID: 11714096
Cardiovascular gene therapy has progressed to the point where clinical trials are now underway, in particular, for peripheral and myocardial ischemia and for restenosis. The delivery vectors are now more...
4.
Obunike J, Lutz E, Li Z, Paka L, Katopodis T, Strickland D, et al.
J Biol Chem
. 2000 Dec;
276(12):8934-41.
PMID: 11121409
Lipoprotein lipase (LPL), the major enzyme responsible for the hydrolysis of circulating lipoprotein triglyceride molecules, is synthesized in myocytes and adipocytes but functions while bound to heparan sulfate proteoglycans (HSPGs)...
5.
Kozarsky K, Donahee M, Glick J, Krieger M, Rader D
Arterioscler Thromb Vasc Biol
. 2000 Mar;
20(3):721-7.
PMID: 10712397
HDL cholesterol levels in humans are inversely correlated with the risk of atherosclerosis. The class B scavenger receptor type I (SR-BI) is the first molecularly well-defined HDL receptor, and hepatic...
6.
Acton S, Kozarsky K, Rigotti A
Mol Med Today
. 1999 Nov;
5(12):518-24.
PMID: 10562717
Although high-density lipoprotein (HDL) metabolism is a crucial process for cholesterol homeostasis and coronary heart disease, therapeutic approaches for selective modification of plasma HDL levels are not currently available. The...
7.
Argraves K, Kozarsky K, Fallon J, HARPEL P, Strickland D
J Clin Invest
. 1997 Dec;
100(9):2170-81.
PMID: 9410893
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity has not been elucidated, but likely involves both its ability to...
8.
Pollack S, Furth E, Kallen C, Arakane F, Kiriakidou M, Kozarsky K, et al.
J Clin Endocrinol Metab
. 1997 Dec;
82(12):4243-51.
PMID: 9398748
The rate-limiting step in steroid hormone production in the adrenal cortex and gonads, the translocation of cholesterol from the outer to the inner mitochondrial membranes, is mediated by the steroidogenic...
9.
10.
Kozarsky K, Donahee M, Rigotti A, Iqbal S, Edelman E, Krieger M
Nature
. 1997 May;
387(6631):414-7.
PMID: 9163428
The risk of atherosclerosis, a leading cause of cardiovascular disease and death, is inversely related to plasma levels of high-density lipoprotein (HDL) cholesterol, although the mechanism of this protective effect...