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K E Callon

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Articles 20
Citations 506
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Recent Articles
1.
Lin J, Callon K, Lin C, Bava U, Zheng M, Reid I, et al.
Eur J Clin Invest . 2007 Apr; 37(5):407-15. PMID: 17461987
Background: Receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoprotegerin (OPG) are well-documented potent regulators of osteoclast development. However, their effects in mature bone cells and in organ cultures have...
2.
Cornish J, Palmano K, Callon K, Watson M, Lin J, Valenti P, et al.
Biochem Cell Biol . 2006 Aug; 84(3):297-302. PMID: 16936800
The maintenance of the mechanical integrity of the skeleton depends on bone remodeling, the well-coordinated balance between bone formation by osteoblasts and bone resorption by osteoclasts. The coupled action of...
3.
Cornish J, Callon K, Bava U, Watson M, Xu X, Lin J, et al.
Am J Physiol Endocrinol Metab . 2006 Aug; 292(1):E117-22. PMID: 16912056
Several hormones that regulate nutritional status also impact on bone metabolism. Preptin is a recently isolated 34-amino acid peptide hormone that is cosecreted with insulin and amylin from the pancreatic...
4.
Cornish J, Gillespie M, Callon K, Horwood N, Moseley J, Reid I
Endocrinology . 2003 Mar; 144(4):1194-201. PMID: 12639900
IL-18 was identified due to its ability to induce interferon-gamma (IFNgamma) production by T cells. It is a pleiotropic factor that shares structural features with IL-1 and functional activities with...
5.
Cornish J, Callon K, Bava U, Lin C, Naot D, Hill B, et al.
J Endocrinol . 2002 Nov; 175(2):405-15. PMID: 12429038
Fat mass is an important determinant of bone density, but the mechanism of this relationship is uncertain. Leptin, as a circulating peptide of adipocyte origin, is a potential contributor to...
6.
Cornish J, Callon K, Bava U, Kamona S, Cooper G, Reid I
Bone . 2001 Aug; 29(2):162-8. PMID: 11502478
Amylin and calcitonin gene-related peptide (CGRP) are homologous 37 amino acid peptides that are found in the circulation. Both peptides belong to the calcitonin family. Similar to calcitonin, amylin and...
7.
Cornish J, Callon K, Bava U, Coy D, Mulvey T, Murray M, et al.
J Endocrinol . 2001 Jun; 170(1):251-7. PMID: 11431158
Adrenomedullin is a 52-amino acid peptide first described in a human phaeochromocytoma but since been found to be present in many tissues, including the vascular system and bone. Because of...
8.
Naot D, Callon K, Grey A, Cooper G, Reid I, Cornish J
Endocrinology . 2001 Apr; 142(5):1849-57. PMID: 11316750
Bone remodeling is a complex process of coordinated resorption and formation of bone, which is regulated by systemic hormones and by local factors. We have previously shown that the peptide...
9.
Cornish J, Callon K, Gasser J, Bava U, Gardiner E, Coy D, et al.
Am J Physiol Endocrinol Metab . 2000 Sep; 279(4):E730-5. PMID: 11001752
Amylin increases bone mass when administered systemically to mice. However, because of its size, the full peptide is not an ideal candidate for the therapy of osteoporosis. The fragment, amylin-(1---8),...
10.
Cornish J, Callon K, Lin C, Xiao C, Mulvey T, Cooper G, et al.
Am J Physiol . 1999 Nov; 277(5):E779-83. PMID: 10567002
Peptides purified by HPLC are often in the form of a trifluoroacetate (TFA) salt, because trifluoroacetic acid is used as a solvent in reversed-phase HPLC separation. However, the potential effects...