K E Callon
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Explore the profile of K E Callon including associated specialties, affiliations and a list of published articles.
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20
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Recent Articles
11.
Cornish J, Callon K, Lin C, Xiao C, Gamble G, Cooper G, et al.
J Bone Miner Res
. 1999 Aug;
14(8):1302-9.
PMID: 10457262
Calcitonin gene-related peptide (CGRP) and amylin are homologous 37-amino-acid peptides which have been demonstrated to have anabolic effects on bone. It is not clear whether these effects are mediated by...
12.
Cornish J, Callon K, Lin C, Xiao C, Moseley J, Reid I
J Bone Miner Res
. 1999 Jun;
14(6):915-22.
PMID: 10352099
Parathyroid hormone (PTH)-related protein (107-139) (PTHrP(107-139)) and PTHrP(107-111) have been reported to be potent inhibitors of isolated osteoclast activity, and inhibition of bone resorption by PTHrP(107-139) occurs in vivo. However,...
13.
Cornish J, Callon K, King A, Cooper G, Reid I
Am J Physiol
. 1998 Oct;
275(4):E694-9.
PMID: 9755090
Amylin is a peptide hormone cosecreted with insulin from the pancreatic beta-cells that can act as an osteoblast mitogen and as an inhibitor of bone resorption. The effects on bone...
14.
Cornish J, Callon K, Lin C, Xiao C, Mulvey T, Coy D, et al.
Am J Physiol
. 1998 Jun;
274(5):E827-33.
PMID: 9612240
This study assesses the structure-activity relationships of the actions of amylin on bone. In fetal rat osteoblasts, only intact amylin and amylin-(1-8) stimulated cell proliferation (half-maximal concentrations 2.0 x 10(-11)...
15.
Cornish J, Callon K, Coy D, Jiang N, Xiao L, Cooper G, et al.
Am J Physiol
. 1998 Jan;
273(6):E1113-20.
PMID: 9435526
Adrenomedullin is a 52-amino acid vasodilator peptide produced in many tissues, including bone. It has 20% sequence identity with amylin, a regulator of osteoblast growth, and circulates in picomolar concentrations....
16.
Cornish J, Callon K, Edgar S, Reid I
Bone
. 1997 Sep;
21(3):243-7.
PMID: 9276089
Leukemia inhibitory factor (LIF) regulates cell growth and is produced by a variety of tissues, including bone. Previously we have shown that recombinant human LIF induced an increase in osteoclast...
17.
Cornish J, Callon K, Nicholson G, Reid I
Endocrinology
. 1997 Mar;
138(3):1299-304.
PMID: 9048639
PTH-related protein-(107-139) [PTHrP-(107-139)] has been reported previously to be a potent inhibitor of osteoclast activity. However, this finding has not been reproduced in other in vitro models. We have now...
18.
Cornish J, Callon K, Reid I
Calcif Tissue Int
. 1996 Dec;
59(6):492-5.
PMID: 8939777
Recent clinical studies have established that bone density is related to both fat mass and circulating insulin levels. A direct action of insulin on the osteoblast may contribute to these...
19.
Cornish J, Callon K, Reid I
Bone
. 1995 Oct;
17(4 Suppl):249S-254S.
PMID: 8579924
The process of bone remodelling is likely to be controlled to a large extent by factors acting locally in a paracrine or autocrine manner, along with some systemic control. In...
20.
Cornish J, Callon K, Cooper G, Reid I
Biochem Biophys Res Commun
. 1995 Feb;
207(1):133-9.
PMID: 7857256
Amylin, a 37-amino-acid peptide co-secreted with insulin from the beta-cells of the pancreatic islets, has previously been demonstrated to inhibit bone resorption in vitro. However, its effects on bone formation...