Jyothi Arikkath
Overview
Explore the profile of Jyothi Arikkath including associated specialties, affiliations and a list of published articles.
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36
Citations
2412
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Recent Articles
1.
Mendez-Vazquez H, Roach R, Nip K, Chanda S, Sathler M, Garver T, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(22):e2300773120.
PMID: 37216537
δ-catenin is expressed in excitatory synapses and functions as an anchor for the glutamatergic AMPA receptor (AMPAR) GluA2 subunit in the postsynaptic density. The glycine 34 to serine (G34S) mutation...
2.
Mendez-Vazquez H, Roach R, Nip K, Sathler M, Garver T, Danzman R, et al.
bioRxiv
. 2023 Jan;
PMID: 36711484
Significance Statement: δ-catenin is important for the localization and function of glutamatergic AMPA receptors at synapses in many brain regions. The glycine 34 to serine (G34S) mutation in the gene...
3.
DeKorver N, Chaudoin T, Zhao G, Wang D, Arikkath J, Bonasera S
Mol Neurobiol
. 2021 Aug;
58(11):5857-5875.
PMID: 34415487
Complement component 3 (C3) expression is increased in the cerebellum of aging mice that demonstrate locomotor impairments and increased excitatory synapse density. However, C3 regulation of locomotion, as well as...
4.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
5.
Baumert R, Ji H, Paulucci-Holthauzen A, Wolfe A, Sagum C, Hodgson L, et al.
J Cell Biol
. 2020 Oct;
219(11).
PMID: 33007084
In neurons, dendrites form the major sites of information receipt and integration. It is thus vital that, during development, the dendritic arbor is adequately formed to enable proper neural circuit...
6.
Arikkath J
Mol Cell Neurosci
. 2020 Jul;
107:103522.
PMID: 32653476
Neurons are highly polarized cells that have specialized regions for synaptic input, the dendrites, and synaptic output, the axons. This polarity is critical for appropriate neural circuit formation and function....
7.
Ligon C, Seong E, Schroeder E, DeKorver N, Yuan L, Chaudoin T, et al.
J Biol Chem
. 2020 Jun;
295(32):10988-11001.
PMID: 32554807
The development of the dendritic arbor in pyramidal neurons is critical for neural circuit function. Here, we uncovered a pathway in which δ-catenin, a component of the cadherin-catenin cell adhesion...
8.
Ligon C, Cai Y, Buch S, Arikkath J
Neurosci Lett
. 2020 May;
730:135048.
PMID: 32439477
Pyramidal neurons have a characteristic morphology that is critical to their ability to integrate into functional neural circuits. In addition to axon dendrite polarity, pyramidal neurons also exhibit dendritic polarity...
9.
Schroeder E, Yuan L, Seong E, Ligon C, DeKorver N, Gurumurthy C, et al.
Mol Neurobiol
. 2018 Oct;
56(6):4151-4162.
PMID: 30288694
CDKL5 disorder is a devastating neurodevelopmental disorder associated with epilepsy, developmental retardation, autism, and related phenotypes. Mutations in the CDKL5 gene, encoding CDKL5, have been identified in this disorder. CDKL5...
10.
Yuan L, Singh D, Buescher J, Arikkath J
J Biol Chem
. 2018 Jun;
293(29):11625-11638.
PMID: 29875160
Neural wiring and activity are essential for proper brain function and behavioral outputs and rely on mechanisms that guide the formation, elimination, and remodeling of synapses. During development, it is...